847062-13-9

Basic information

• Product Name: 5-Pyrimidinecarboxylic acid, 1,4-dihydro-6-methyl-4-(4-methylphenyl)-2-(methylthio)-, ethyl ester
• CAS NO: 847062-13-9
• Molecular Formula: C16H20N2O2S
• Molecular Weight: 304.413
• Mol File: 847062-13-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-Pyrimidinecarboxylic acid, 1,4-dihydro-6-methyl-4-(4-methylphenyl)-2-(methylthio)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarboxylic acid, 1,4-dihydro-6-methyl-4-(4-methylphenyl)-2-(methylthio)-, ethyl ester(847062-13-9)
• EPA Substance Registry System: 5-Pyrimidinecarboxylic acid, 1,4-dihydro-6-methyl-4-(4-methylphenyl)-2-(methylthio)-, ethyl ester(847062-13-9)

Safety Data

• Hazardous Substances Data: 847062-13-9(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 185023-34-1 5-carboethoxy-6-methyl-4-(4-methylphenyl)-1H-pyrimidin-2-thione 
• 74-88-4 methyl iodide 
• 104-87-0 4-methyl-benzaldehyde 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 1117816-29-1 C₃₁H₂₅ClN₄O₄ 
• 1236204-31-1 ethyl 4-methyl-2-(methylthio)-6-p-tolylpyrimidine-5-carboxylate 
• 1412900-77-6 ethyl 3-(5-bromo-benzofuran-2-carbonyl)-7-methyl-1-phenyl-5-p-tolyl-1,5-dihydro-[1,2,4]triazolo[4,3-a]pyrimidine-6-carboxylate 

Relevant articles and documents

Novel pyrimidinic selenourea induces DNA damage, cell cycle arrest, and apoptosis in human breast carcinoma

Novel pyrimidinic selenoureas were synthesized and evaluated against tumour and normal cell lines. Among these, the compound named 3j initially showed relevant cytotoxicity and selectivity for tumour cells. Three analogues of 3j were designed and synthesi

Synthesis and anti-hypertensive activity of some dihydropyrimidines

Wide range of biological activities are associated with 1,4-dihydropyridines/pyrimidines, individually or in combination. In view of the synthesis of various 6-methyl-4-substitutedphenyl-2-thioxo-1,2,3,4- tetrahydropyrimidine-5-carboxylic acid ethyl esters and 6-methyl-4-substituted phenyl-2-S-alkyl(benzyl)-1,4-dihydropyrimidine-5-carboxylic acid ethyl esters was undertaken for synthesizing biologically active molecules with improved activity, lesser toxicity with undesirable side effects in clinical use. The synthesized compounds have been tested for anti-hypertensive activity and show some new results about the structure-activity relationship contrary to an earlier reports.