847851-60-9

Basic information

• Product Name: C₂₂H₂₆N₂O₂
• CAS NO: 847851-60-9
• Molecular Weight: 350.461
• Mol File: 847851-60-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₆N₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₆N₂O₂(847851-60-9)
• EPA Substance Registry System: C₂₂H₂₆N₂O₂(847851-60-9)

Safety Data

• Hazardous Substances Data: 847851-60-9(Hazardous Substances Data)

Upstream product

• 1006-94-6 5-methoxylindole 
• 608-07-1 2-(5-methoxyindol-3-yl)ethylamine 
• 1710-98-1 p-tert-butyl benzoyl chloride 
• 61675-19-2 5-methoxy-3-(2-nitroethylenyl)-1H-indole 
• 10601-19-1 5-methoxyindole-3-carboxaldehyde 

Relevant articles and documents

Chiral anion phase transfer of aryldiazonium cations: An enantioselective synthesis of C3-diazenated pyrroloindolines

Herein is reported the first asymmetric utilization of aryldiazonium cations as a source of electrophilic nitrogen. This is achieved through a chiral anion phase-transfer pyrroloindolinization reaction that forms C3-diazenated pyrroloindolines from simple tryptamines and aryldiazonium tetrafluoroborates. The title compounds are obtained in up to 99% yield and 96% ee. The air- and water-tolerant reaction allows electronic and steric diversity of the aryldiazonium electrophile and the tryptamine core. Live and let diazene: Chiral anion phase transfer of aryldiazonium cations has been utilized to prepare C3-diazenated pyrroloindolines. The air- and water-tolerant reaction allows electronic and steric diversity in the aryldiazonium electrophile and the tryptamine core, with the products being obtained in up to 99% yield and 96% ee (MTBE=methyl tert-butyl ether).