848215-13-4

Basic information

• Product Name: 3-Oxazolidinecarboxylic acid, 4-[3-[(4-nitrophenyl)amino]-3-oxopropyl]-5-oxo-, phenylmethyl ester, (4S)-
• CAS NO: 848215-13-4
• Molecular Formula: C20H19N3O7
• Molecular Weight: 413.387
• Mol File: 848215-13-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Oxazolidinecarboxylic acid, 4-[3-[(4-nitrophenyl)amino]-3-oxopropyl]-5-oxo-, phenylmethyl ester, (4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxazolidinecarboxylic acid, 4-[3-[(4-nitrophenyl)amino]-3-oxopropyl]-5-oxo-, phenylmethyl ester, (4S)-(848215-13-4)
• EPA Substance Registry System: 3-Oxazolidinecarboxylic acid, 4-[3-[(4-nitrophenyl)amino]-3-oxopropyl]-5-oxo-, phenylmethyl ester, (4S)-(848215-13-4)

Safety Data

• Hazardous Substances Data: 848215-13-4(Hazardous Substances Data)

Upstream product

• 58456-26-1 (S)-4-<2'-(Chloroformyl)ethyl>-5-oxooxazolidin-3-carbonsaeure-benzylester 
• 100-01-6 4-nitro-aniline 
• 23632-67-9 (S)-3-[3-(benzyloxycarbonyl)-5-oxooxazolidin-4-yl]propanoic acid 
• 1155-62-0 N-benzyloxycarbonyl-L-glutamic acid 
• 56-86-0 L-glutamic acid 

Downstream Products

• 7300-59-6 L-glutamic acid 5-(4-nitroanilide) 
• 113277-32-0 (S)-2-Benzyloxycarbonylamino-4-(4-nitro-phenylcarbamoyl)-butyric acid 

Relevant articles and documents

Nγ-Aryl glutamine analogues as probes of the ASCT2 neutral amino acid transporter binding site

Analogues of l-glutamine were designed and synthesized to test a hydrogen-bond hypothesis between ligand and neutral amino acid transporter ASCT2. The key design feature contains a substituted phenyl ring on the amide nitrogen that contains electron withdrawing and electron donating groups that alter the pKa of the amide NH. Through this study a preliminary binding site map has been developed, and a potent commercially available competitive inhibitor of the ASCT2 transporter has been identified.