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84828-97-7

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  • 1-((6aR,8R,9aR)-2,2,4,4-Tetraisopropyl-9-oxotetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)pyrimidine-2,4(1H,3H)-dione

    Cas No: 84828-97-7

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  • 1-((6aR,8R,9aR)-2,2,4,4-tetraisopropyl-9-oxotetrahydro-6H-furo[3,2-f ][1,3,5,2,4]trioxadisilocin-8-yl)pyrimidine-2,4(1H,3H)-dione

    Cas No: 84828-97-7

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  • Watson International Ltd
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84828-97-7 Usage

Description

1-((6aR,8R,9aR)-2,2,4,4-tetraisopropyl-9-oxotetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)pyrimidine-2,4(1H,3H)-dione is a complex organic compound with a unique fused ring structure. It contains silicon, oxygen, carbon, hydrogen, and nitrogen atoms, and is a pyrimidine derivative with a tetrahydrofuran ring and four isopropyl groups. 1-((6aR,8R,9aR)-2,2,4,4-tetraisopropyl-9-oxotetrahydro-6H-furo[3,2-f ][1,3,5,2,4]trioxadisilocin-8-yl)pyriMidine-2,4(1H,3H)-dione is primarily used in organic and medicinal chemistry research.

Uses

Used in Organic Chemistry Research:
1-((6aR,8R,9aR)-2,2,4,4-tetraisopropyl-9-oxotetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)pyrimidine-2,4(1H,3H)-dione is used as a research compound in organic chemistry for studying its chemical properties and potential applications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1-((6aR,8R,9aR)-2,2,4,4-tetraisopropyl-9-oxotetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)pyrimidine-2,4(1H,3H)-dione is used for investigating its potential as a drug candidate. Its unique structure and composition may contribute to various pharmacological activities, which can be further explored for the development of new therapeutic agents.
Used in Drug Development:
1-((6aR,8R,9aR)-2,2,4,4-tetraisopropyl-9-oxotetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)pyrimidine-2,4(1H,3H)-dione may have potential applications in drug development due to its complex structure and the presence of multiple functional groups. Further research is needed to fully understand its properties and explore its potential uses in the development of new drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 84828-97-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,4,8,2 and 8 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 84828-97:
(7*8)+(6*4)+(5*8)+(4*2)+(3*8)+(2*9)+(1*7)=177
177 % 10 = 7
So 84828-97-7 is a valid CAS Registry Number.

84828-97-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(6aR,8R,9aR)-9-oxo-2,2,4,4-tetrakis(propan-2-yl)-hexahydro-2H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:84828-97-7 SDS

84828-97-7Downstream Products

84828-97-7Relevant articles and documents

A double-headed nucleotide with two cytosines: DNA with condensed information and improved duplex stability

Beck, Kasper,Reslow-Jacobsen, Charlotte,Hornum, Mick,Henriksen, Christian,Nielsen, Poul

, p. 740 - 743 (2019)

Double-headed nucleotide monomers are capable of condensing the genetic information of DNA. Herein, a double-headed nucleotide with two cytosine bases (CC) is constructed. The additional cytosine is connected through a methylene linker to the 2

Synthesis of 2'-deoxy-2'-spirocyclopropyl cytidine as potential inhibitor of ribonucleotide diphosphate reductase

Czernecki,Mulard,Valery,Commercon

, p. 413 - 416 (1993)

-

New insight into the mechanism of base propenal formation during bleomycin-mediated DNA degradation

McGall,Rabow,Ashley,Wu,Kozarich,Stubbe

, p. 4958 - 4967 (1992)

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Nucleosides and Nucleotides. 102. Stereoselective Radical Deoxygenation of Tert-Propargyl Alcohols in Sugar Moiety of Pyrimidine Nucleosides: Synthesis of 2'-C-Alkynyl-2'-Deoxy-1-β-D-Arabinofuranosylpyrimidines

Yoshimura, Yuichi,Iino, Tomoharu,Matsuda, Akira

, p. 6003 - 6006 (1991)

Synthesis of the title compounds can be achieved by nucleophilic addition of lithium salts of TMSacetylene and 1-hexyne to 2'-ketouridine followed by radical deoxygenation of the corresponding methoxyaryl ester.Key Words: radical deoygenation; propargyl alcohol; ethynyl substituent; acetylene

Base-Pairing Properties of Double-Headed Nucleotides

Hornum, Mick,Stendevad, Julie,Sharma, Pawan K.,Kumar, Pawan,Nielsen, Rasmus B.,Petersen, Michael,Nielsen, Poul

, p. 7387 - 7395 (2019/05/16)

Nucleotides that contain two nucleobases (double-headed nucleotides) have the potential to condense the information of two separate nucleotides into one. This presupposes that both bases must successfully pair with a cognate strand. Here, double-headed nucleotides that feature cytosine, guanine, thymine, adenine, hypoxanthine, and diaminopurine linked to the C2′-position of an arabinose scaffold were developed and examined in full detail. These monomeric units were efficiently prepared by convergent synthesis and incorporated into DNA oligonucleotides by means of the automated phosphoramidite method. Their pairing efficiency was assessed by UV-based melting-temperature analysis in several contexts and extensive molecular dynamics studies. Altogether, the results show that these double-headed nucleotides have a well-defined structure and invariably behave as functional dinucleotide mimics in DNA duplexes.

Novel 2'-fluorouracil nucleoside and synthetic method

-

Paragraph 0014, (2019/01/05)

The invention discloses a novel 2'-fluorouracil nucleoside and a synthetic method. A structural general formula of a compound is shown as the specification, and the synthetic method comprises the following steps in the specification. The synthesis method

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