84907-66-4Relevant articles and documents
Fast and Efficient Continuous Flow Method for the Synthesis of Ynones and Pyrazoles
Kandasamy, Mohanraj,Ganesan, Balaji,Hung, Min-Yuan,Lin, Wei-Yu
, p. 3183 - 3189 (2019)
In this study, we developed a convenient and efficient two-step method for the synthesis of ynones in a flow reactor, through the generation of lithium acetylide and its subsequent reactions with acid chlorides. Using this approach, we obtained the ynones in moderate to good yields at room temperature. Moreover, we transformed the ynones into pyrazole derivatives through coupling with hydrazines. This transition metal-free process, mild reaction conditions, and broad functional group tolerance are all attractive features in comparison with conventional bench-top methods.
Triorganothallium Reagents in Organic Chemistry. 1. A Simple, Efficient, and Versatile Preparation of Ketones from Acid Chlorides
Marko, Istvan E.,Southern, J. Mike
, p. 3368 - 3370 (2007/10/02)
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A NOVEL METHOD FOR THE SYNTHESIS OF ALKYNYL KETONES - A REACTION OF ALKYNYL BORANES WITH AMIDES
Yamaguchi, Masahiko,Waseda, Toshie,Hirao, Ichiro
, p. 35 - 36 (2007/10/02)
Alkynyl ketones are synthesized in high yields by the reaction of alkynyl boranes and amides under a mild reaction condition.