849354-92-3Relevant articles and documents
Fine-tuning furan toxicity: Fast and quantitative DNA interchain cross-link formation upon selective oxidation of a furan containing oligonucleotide
Halila, Sami,Velasco, Trinidad,De Clercq, Pierre,Madder, Annemieke
, p. 936 - 938 (2005)
Oligonucleotides containing a furan modified internal nucleoside have been synthesized; selective in situ oxidation of the furan moiety to a reactive enal species in the presence of a complementary DNA strand gives rise to fast and efficient formation of an interstrand cross-link. The Royal Society of Chemistry 2005.