935-13-7

Basic information

• Product Name: 3-(2-FURYL)PROPANOIC ACID
• Synonyms: TIMTEC-BB SBB005449;3-(2-FURYL)PROPANOIC ACID;3-(2-FURYL)PROPIONIC ACID;2-FURANPROPANOIC ACID;2-FURANPROPIONIC ACID;3-FURAN-2-YL-PROPIONIC ACID;AKOS AU36-M219;furan-2-propionic acid
• CAS NO: 935-13-7
• Molecular Formula: C₇H₈O₃
• Molecular Weight: 140.14
• EINECS: 213-298-4
• Product Categories: Carboxylic Acids;Furans, Benzofurans & Dihydrobenzofurans;API intermediates;Carboxylic Acids;Furans, Benzofurans & Dihydrobenzofurans;Building Blocks;C4 to C7;Chemical Synthesis;Furans;Heterocyclic Building Blocks
• Mol File: 935-13-7.mol
• Article Data: 19

Chemical Properties

• Melting Point: 56-59 °C
• Boiling Point: 229
• Flash Point: 103 °C
• Appearance: Almost white to brown/Crystalline Powder
• Density: 1.2127 (rough estimate)
• Vapor Pressure: 0.04mmHg at 25°C
• Refractive Index: 1.4638 (estimate)
• Storage Temp.: Refrigerator (+4°C)
• PKA: 4.51±0.10(Predicted)
• CAS DataBase Reference: 3-(2-FURYL)PROPANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-FURYL)PROPANOIC ACID(935-13-7)
• EPA Substance Registry System: 3-(2-FURYL)PROPANOIC ACID(935-13-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-41-37/38
• Safety Statements: 37/39-26-39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 935-13-7(Hazardous Substances Data)

Usage

Chemical Properties

almost white to brown crystalline powder

InChI:InChI=1/C7H8O3/c8-7(9)4-3-6-2-1-5-10-6/h1-2,5H,3-4H2,(H,8,9)/p-1

Upstream product

• 63825-24-1 2-(2-chloro-ethyl)-furan 
• 4543-51-5 3-(2-furyl)propionaldehyde 
• 2745-27-9 2-(furan-2-yl)acetic acid chloride 
• 90111-44-7 [2]furyl-succinic acid 
• 4440-15-7 furfuryl-malonic acid 
• 539-47-9 3-(fur-2-yl)crotonic acid 
• 119-64-2 tetralin 
• 121-69-7 N,N-dimethyl-aniline 
• 10031-90-0 ethyl 3-(furan-2-yl)propanoate 
• 98-01-1 furfural 
• 4440-16-8 2-(2-furanylmethylene)-propanedioic acid 
• 17448-96-3 ethyl 2-carbethoxy-3-(2-furanyl)propenoate 
• 539-47-9 3-(2-furyl)acrylic acid 
• 26908-23-6 3-furan-2-yl-propan-1-ol 

Downstream Products

• 37493-31-5 methyl 3-(2-furyl)propionate 
• 26908-23-6 3-furan-2-yl-propan-1-ol 
• 849354-88-7 pentafluorophenyl-3-(2-furyl)-propanoate 
• 311803-97-1 (4R,5S)-3-(3-Furan-2-yl-propionyl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 311804-05-4 (4S,5R)-3-(3-Furan-2-yl-propionyl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 908138-98-7 N-(1-{5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-furan-2-yl-propionamide 
• 10031-90-0 ethyl 3-(furan-2-yl)propanoate 
• 311804-09-8 (R)-4-(furan-2-yl)-3-(toluene-4-sulfonyloxymethyl)butyric acid tert-butyl ester 
• 311804-01-0 (S)-4-(furan-2-yl)-3-(toluene-4-sulfonyloxymethyl)-butyric acid tert-butyl ester 
• 311803-98-2 (S)-3-Furan-2-ylmethyl-4-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-yl)-4-oxo-butyric acid tert-butyl ester 
• 311804-06-5 (R)-3-Furan-2-ylmethyl-4-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-yl)-4-oxo-butyric acid tert-butyl ester 
• 827598-78-7 3-furan-2-yl-N-(6-methyl-pyridin-2-yl)-propionamide 
• 849354-92-3 1-{2-deoxy-5-O-(dimethoxytrityl)-2-(2-furyl-2-ethoxycarbonylamino)-β-D-arabinofuranosyl} uracil 

Relevant articles and documents

Furan-PNA: A mildly inducible irreversible interstrand crosslinking system targeting single and double stranded DNA

We here report on the design and synthesis of tailor-made furan-modified peptide nucleic acid (PNA) probes for covalent targeting of single stranded DNA through a crosslinking strategy. After introducing furan-containing building blocks into a PNA sequence, hybridization and furan-oxidation based crosslinking to DNA is investigated. The structure of the crosslinked products is characterized and preliminary investigations concerning the application of these systems to double stranded DNA are shown.

Metal-Free Chemoselective Oxidative Dehomologation or Direct Oxidation of Alcohols: Implication for Biomass Conversion

A transition metal-free, chemoselective reaction was performed using the sodium tert-butoxide-oxygen (NaOtBu-O2) system, resulting in either oxidative dehomologation or direct oxidation of alcohols. In particular, the newly developed protocol may be used to predict the major product formed, which depends on alkyl chain length of the alcohols and reaction conditions. The rational mechanism of this transformation was also demonstrated by performing an 18O isotopic labelling experiment. This protocol presents a straightforward method for biomass conversion of a lignin model compound to phenol and benzoic acid.

Raney nickel-catalyzed hydrogenation of unsaturated carboxylic acids with sodium borohydride in water

A mild, selective, and green method for the reduction of unsaturated carboxylic acids with sodium borohydride-Raney nickel (W6) system in water is reported. This method is practical and safe and avoids use of organic solvents. Taylor & Francis Group, LLC.