849405-73-8Relevant articles and documents
Steric effects on deprotonative generation of cyclohexynes and 1,2-cyclohexadienes from cyclohexenyl triflates by magnesium amides
Hioki, Yuto,Mori, Atsunori,Okano, Kentaro
, (2020/04/28)
Steric effects on the deprotonative generation of cyclohexynes and 1,2-cyclohexadienes from cyclohexenyl triflates are described. A cyclohexenyl triflate, which is readily available from nonsubstituted cyclohexanone, was selectively converted to cyclohexy
Enantioselective [2 + 2] cycloaddition of unactivated alkenes with α-acyloxyacroleins catalyzed by chiral organoammonium salts
Ishihara, Kazuaki,Nakano, Kazuhiko
, p. 8930 - 8931 (2008/02/10)
We report the first example of an organocatalytic enantioselective [2 + 2] cycloaddition reaction of unactivated alkenes with α-acyloxyacroleins to give optically active 1-acyloxycyclobutanecarbaldehydes and subsequent ring expansion to give optically active 2-hydroxycyclopentanone derivatives. Organoammonium salt, H-L-Phe-L-Leu-N(CH2CH2)2-reduced triamine?2.6HNTf2, is a highly effective chiral catalyst for the above enantioselective [2 + 2] cycloaddition. Thus, we have developed a novel and useful formal enantioselective [2 + 3] cycloaddition through two steps. Copyright
