85059-48-9

Basic information

• Product Name: 2-ISOCYANO-3-PHENYL-PROPIONIC ACID MORPHOLINAMIDE
• Synonyms: 2-ISOCYANO-3-PHENYL-PROPIONIC ACID MORPHOLINAMIDE;2-isocyano-1-morpholin-4-yl-3-phenylpropan-1-one
• CAS NO: 85059-48-9
• Molecular Formula: C₁₄H₁₆N₂O₂
• Molecular Weight: 244.29
• Mol File: 85059-48-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-ISOCYANO-3-PHENYL-PROPIONIC ACID MORPHOLINAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ISOCYANO-3-PHENYL-PROPIONIC ACID MORPHOLINAMIDE(85059-48-9)
• EPA Substance Registry System: 2-ISOCYANO-3-PHENYL-PROPIONIC ACID MORPHOLINAMIDE(85059-48-9)

Safety Data

• Hazardous Substances Data: 85059-48-9(Hazardous Substances Data)

Upstream product

• 120301-87-3 N-(1-benzyl-2-morpholin-4-yl-2-oxo-ethyl)formamide 
• 100-39-0 benzyl bromide 
• 67434-29-1 isocyanoacetylmorpholine 
• 150-30-1 Phenylalanine 
• 71921-02-3 2-benzyl-2-formamidoacetic acid methyl ester 

Downstream Products

• 336105-97-6 6-[1-(4-benzyl-5-morpholin-4-yl-oxazol-2-yl)-heptylamino]-hexanoic acid methyl ester 
• 336105-90-9 [1-(4-benzyl-5-morpholin-4-yl-oxazol-2-yl)-heptyl]-[2-(3,4-dimethoxy-phenyl)-ethyl]-amine 
• 336105-94-3 [1-(4-benzyl-5-morpholin-4-yl-oxazol-2-yl)-butyl]-(4-methoxy-benzyl)-amine 
• 336105-92-1 [1-(4-benzyl-5-morpholin-4-yl-oxazol-2-yl)-heptyl]-(3-methyl-benzyl)-amine 
• 336105-96-5 [(4-benzyl-5-morpholin-4-yl-oxazol-2-yl)-cyclooctyl-methyl]-(4-fluoro-benzyl)-amine 
• 411222-61-2 [1-(4-benzyl-5-morpholin-4-yl-oxazol-2-yl)-heptyl]-butyl-amine 

Relevant articles and documents

Divergent Synthesis of Enantioenriched β-Functional Amines via Desymmetrization of meso-Aziridines with Isocyanides

A highly enantioselective ring-opening desymmetrization of meso-aziridines with isocyanides was achieved in the presence of a chiral N,N′-dioxide/Mg(OTf)2 complex. The in situ generated chiral 1,4-zwitterionic intermediates were successfully trapped by intramolecular oxygen- and carbon-based nucleophiles or exogenous H2O and TMSN3, enabling a collective synthesis of various chiral vicinal amino-oxazoles, spiroindolines, β-amino amides, and tetrazole derivative in moderate to high yields with excellent enantioselectivities.

Substituted Oxazole Compounds with Analgesic Activity

Substituted oxazole derivatives corresponding to formula 1: a method for producing such compounds, pharmaceutical compositions containing such compounds, and the use of such compounds to treat pain, depression, urinary incontinence, diarrhoea, pruritus, a

Multicomponent synthesis of epoxy-tetrahydronaphthyridine and structural diversification by subsequent fragmentation

Three-component reaction of an α-isocyanoacetamide 7, an homoallylamine 8 and an aldehyde 9 in methanol at room temperature provides oxa-bridged tricycle 4 in good to excellent yield as a mixture of two separable diastereoisomers. In this one-pot multicom