85098-68-6

Basic information

• Product Name: 2-[(4-fluorophenyl)amino]acetamide
• Synonyms: 2-[(4-fluorophenyl)amino]acetamide;Einecs 285-419-9;N~2~-(4-fluorophenyl)glycinamide
• CAS NO: 85098-68-6
• Molecular Formula: C₈H₉FN₂O
• Molecular Weight: 168.1682632
• EINECS: 285-419-9
• Mol File: 85098-68-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 382.3°C at 760 mmHg
• Flash Point: 185°C
• Appearance: /
• Density: 1.289g/cm³
• Vapor Pressure: 4.76E-06mmHg at 25°C
• Refractive Index: 1.59
• CAS DataBase Reference: 2-[(4-fluorophenyl)amino]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(4-fluorophenyl)amino]acetamide(85098-68-6)
• EPA Substance Registry System: 2-[(4-fluorophenyl)amino]acetamide(85098-68-6)

Safety Data

• Hazardous Substances Data: 85098-68-6(Hazardous Substances Data)

Usage

Chemical classification

Amide derivative

Parent compound

4-fluoroaniline

Common use

Precursor in the synthesis of pharmaceuticals and agrochemicals

Physical appearance

White to light tan solid

Solubility

Sparingly soluble in water

Stability

Stable under normal conditions

Utilization

Organic synthesis as a building block for functionalized molecules

Potential applications

Development of new drugs and agrochemicals

Reactivity

Ability to react with various reagents and form chemical derivatives

InChI:InChI=1/C8H9FN2O/c9-6-1-3-7(4-2-6)11-5-8(10)12/h1-4,11H,5H2,(H2,10,12)

Downstream Products

• 351-95-1 N-(4-fluoro-phenyl)-glycine 

Relevant articles and documents

Process for producing optically active alpha-amino acid and optically active alpha-amino acid amine

The present invention provides a process for efficiently producing an optically active α-amino acid and an optically active α-amino acid amide. After contacting with cells or processed cells thereof having an ability to asymmetrically hydrolyse, a water solvent is substituted with at least one solvent selected from the group consisting of linear, branched, or cyclic alcohol having 3 or more carbon atoms and the optically active α-amino acid is preferentially precipitated from the alcohol solution. The addition of basic compounds, particularly potassium compounds to the alcohol solution containing the optically active α-amino acid amide, which is obtained after the separation of the optically active α-amino acid, enables the purification of the amide without the inclusion of amino acid into amino acid amide. Thus, the amide is subjected to the step of racemization and then recycled.