852286-99-8

Basic information

• Product Name: N'-[4-(1,2,2,6,6-pentamethyl-piperidin-4-yl-carbamoyl)-phenyl]-hydrazinecarboxylic acid ter-butyl ester
• Synonyms: N'-[4-(1,2,2,6,6-pentamethyl-piperidin-4-yl-carbamoyl)-phenyl]-hydrazinecarboxylic acid ter-butyl ester
• CAS NO: 852286-99-8
• Molecular Weight: 404.553
• Mol File: 852286-99-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N'-[4-(1,2,2,6,6-pentamethyl-piperidin-4-yl-carbamoyl)-phenyl]-hydrazinecarboxylic acid ter-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N'-[4-(1,2,2,6,6-pentamethyl-piperidin-4-yl-carbamoyl)-phenyl]-hydrazinecarboxylic acid ter-butyl ester(852286-99-8)
• EPA Substance Registry System: N'-[4-(1,2,2,6,6-pentamethyl-piperidin-4-yl-carbamoyl)-phenyl]-hydrazinecarboxylic acid ter-butyl ester(852286-99-8)

Safety Data

• Hazardous Substances Data: 852286-99-8(Hazardous Substances Data)

Upstream product

• 96736-00-4 4-(2-(tert-butoxycarbonyl)hydrazineyl)benzoic acid 
• 40327-96-6 4-amino-1,2,2,6,6-pentamethylpiperidine 

Downstream Products

• 852287-00-4 4-hydrazino-N-(1,2,2,6,6-pentamethyl-piperidin-4-yl)-benzamide 

Relevant articles and documents

IMMUNO INHIBITORY PYRAZOLONE COMPOUNDS

Compounds of formula (IA) or (IB) are inhibitors of CD80 and useful in immunomodulation therapy: wherein Ar represents an optionally substituted monocyclic or bicyclic aromatic or heteroaromatic group having from 5 to 10 ring atoms; R1 and R2 independently represent H, or Cl-C6 alkyl; R3 represents H; F; CI; Br; -NO2; - CN; C1-C6 alkyl optionally substituted by F or CI; or C1-C6 alkoxy optionally substituted by F; R4 represents a carboxylic acid group (-COOH) or an ester thereof, or -C(=O)NR6R7, -NR7C(=O)R6, -NR7C(=O)OR6, -NHC(=O)NR7R6 or -NHC(=S)NR7R6 wherein R6 represents H, or a radical of formula -(Alk)m-Q wherein m is 0 or 1, Alk is an optionally substituted divalent straight or branched C1-C12 alkylene, or C2-C12 alkenylene, or C2-C12 alkynylene radical or a divalent C3-C12 carbocyclic radical, any of which radicals may be interrupted by one or more -0-, -S- or -N(R8)- radicals wherein R8 represents H or C1-C4 alkyl, C3-C4 alkenyl, C3-C4 alkynyl, or C3-C6 cycloalkyl, and Q represents H; -CF3;-OH; -SH; -NR8R8wherein each R8 may be the same or different, or form a ring when taken together with the nitrogen to which they are attached; an ester group; or an optionally substituted aryl, aryloxy, cycloalkyl, cycloalkenyl or heterocyclic group; and R7 represents H or C1-C6 alkyl; or when taken together with the atom or atoms to which they are attached R6 and R7 form a monocyclic heterocyclic ring having 5, 6 or 7 ring atoms; and X represents a bond or a divalent radical of formula -(Z)n-(Alk)- or -(Alk)-(Z)n- wherein Z represents -0-, -S- or -NH-, Alk is as defined in relation to R6 and n is 0 or 1.