96736-00-4

Basic information

• Product Name: 4-(2'-N-BOC-HYDRAZINO)BENZOIC ACID
• Synonyms: BOC-4-HYDRAZINOBENZOIC ACID;BOC-NH-ABZ(4)-OH;4-(2'-N-BOC-HYDRAZINO)BENZOIC ACID;4-(BOC-HYDRAZINO)-BENZOIC ACID;4-(N'-BOC-HYDRAZINO)-BENZOIC ACID;4-(T-BUTOXYCARBONYL-HYDRAZINO)-BENZOIC ACID;4-(2-(tert-Butoxycarbonyl)hydrazinyl)benzoic acid;4-[2-(tert-Butoxycarbonyl)hydrazino]benzoic acid
• CAS NO: 96736-00-4
• Molecular Formula: C₁₂H₁₆N₂O₄
• Molecular Weight: 252.27
• Mol File: 96736-00-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(2'-N-BOC-HYDRAZINO)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2'-N-BOC-HYDRAZINO)BENZOIC ACID(96736-00-4)
• EPA Substance Registry System: 4-(2'-N-BOC-HYDRAZINO)BENZOIC ACID(96736-00-4)

Safety Data

• Hazardous Substances Data: 96736-00-4(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 619-67-0 4-Hydrazinobenzoic acid 
• 24589-77-3 4-hydrazinobenzoic acid hydrochloride 

Downstream Products

• 852286-99-8 N'-[4-(1,2,2,6,6-pentamethyl-piperidin-4-yl-carbamoyl)-phenyl]-hydrazinecarboxylic acid ter-butyl ester 
• 848083-52-3 (4-{[(tert-butoxy)carbonylamino]amino}phenyl)-N-{2-[(phenylmethoxy)carbonylamino]ethyl}carboxamide 
• 848083-55-6 (2S)-N-({4-[N-(2-aminoethyl)carbamoyl]phenyl}amino)-2-[(tert-butoxy)carbonylamino]-4-methylpentanamide 
• 848083-51-2 C₂₈H₃₄N₈O₆S 

Relevant articles and documents

Tyrosine-Specific Modification via a Dearomatization-Rearomatization Strategy: Access to Azobenzene Functionalized Peptides

Azobenzene functionalized peptides are of great importance in photoresponsive biosystems and photopharmacology. Herein, we report an efficient approach to prepare azobenzene functionalized peptides through late-stage modification of tyrosine-containing peptides using a dearomatization-rearomatization strategy. This approach shows good chemoselectivity and site selectivity as well as sensitive group tolerance to various peptides. This method enriches the postsynthetic modification toolbox of peptides and has great potential to be applied in medicinal chemistry and chemical biology.

3,5-BIS(PHENYL)-1H-HETEROARYL DERIVATIVES AS MEDICAMENTS

The present invention claims compounds of general formula I: wherein the meaning of individual substituents is described in the claims. The compounds are useful in treatment of cancers, due to their multi-modal mechanism of action.

NOVEL AZAPEPTIDE OR AZAPEPTIDOMIMETIC COMPOUNDS INHIBITING BCRP AND/OR P-GP

The present invention relates to compounds of azapeptide or azapeptidomimetic type of formula (I): in which R1, R2, R3, X1, X2, X3, X4 and Y are as defined in claim 1, to pharmaceutical compositions containing them and to such compounds as adjuvant for an anticancer or anti-infectious medicament.