852608-62-9

Basic information

• Product Name: 2-(2-fluoro-phenyl)-7-methoxy-benzofuran-4-carbaldehyde
• CAS NO: 852608-62-9
• Molecular Weight: 270.26
• Mol File: 852608-62-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-fluoro-phenyl)-7-methoxy-benzofuran-4-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-fluoro-phenyl)-7-methoxy-benzofuran-4-carbaldehyde(852608-62-9)
• EPA Substance Registry System: 2-(2-fluoro-phenyl)-7-methoxy-benzofuran-4-carbaldehyde(852608-62-9)

Safety Data

• Hazardous Substances Data: 852608-62-9(Hazardous Substances Data)

Upstream product

• 20035-41-0 6-bromo-2-hydroxy-3-methoxybenzaldehyde 
• 35090-65-4 6-bromo-2-hydroxy-3-methoxybenzyl alcohol 
• 68-12-2 N,N-dimethyl-formamide 

Relevant articles and documents

Novel 4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)methylbenzofuran derivatives as selective α2C-adrenergic receptor antagonists

The synthesis of a series of 4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)methyl-2-arylbenzofuran and 4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)methylbenzofuran-2-carboxamide derivatives as novel α2C-adrenergic receptor antagonists are described. Their affinity at three different human α2-adrenergic receptors is reported, and some of these compounds exhibited high affinity for the α2C-adrenergic receptor with high subtype selectivity. Among them, compound 10e has been found to show the anti-l-dopa-induced dyskinetic activity in marmosets. The structure-activity relationship of these compounds is also discussed.