853400-82-5

Basic information

• Product Name: (S)-2-[((S)-2-Methyl-pyrrolidine-2-carbonyl)-amino]-pentanedioic acid dibenzyl ester
• CAS NO: 853400-82-5
• Molecular Weight: 438.524
• Mol File: 853400-82-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-[((S)-2-Methyl-pyrrolidine-2-carbonyl)-amino]-pentanedioic acid dibenzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-[((S)-2-Methyl-pyrrolidine-2-carbonyl)-amino]-pentanedioic acid dibenzyl ester(853400-82-5)
• EPA Substance Registry System: (S)-2-[((S)-2-Methyl-pyrrolidine-2-carbonyl)-amino]-pentanedioic acid dibenzyl ester(853400-82-5)

Safety Data

• Hazardous Substances Data: 853400-82-5(Hazardous Substances Data)

Upstream product

• 103336-06-7 N-(tert-butoxycarbonyl)-2-methyl-L-proline 
• 2768-50-5 dibenzyl L-glutamate 

Downstream Products

• 853400-76-7 glycyl-L-2-methylprolyl-L-glutamic acid 
• 869001-94-5 dibenzyl N-benzyloxycarbonyl-glycyl-L-2-methylprolyl-L-glutamate 

Relevant articles and documents

Analogues of the neuroprotective tripeptide Gly-Pro-Glu (GPE): Synthesis and structure-activity relationships

A series of GPE analogues, including modifications at the Pro and/or Glu residues, was prepared and evaluated for their NMDA binding and neuroprotective effects. Main results suggest that the pyrrolidine ring puckering of the Pro residue plays a key role