853678-27-0

Basic information

• Product Name: (2R)-2-amino-3-phenyl-1-(4-quinazolin-4-yl-piperazin-1-yl)-propan-1-one
• Synonyms: (2R)-2-amino-3-phenyl-1-(4-quinazolin-4-yl-piperazin-1-yl)-propan-1-one
• CAS NO: 853678-27-0
• Molecular Weight: 361.447
• Mol File: 853678-27-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R)-2-amino-3-phenyl-1-(4-quinazolin-4-yl-piperazin-1-yl)-propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-amino-3-phenyl-1-(4-quinazolin-4-yl-piperazin-1-yl)-propan-1-one(853678-27-0)
• EPA Substance Registry System: (2R)-2-amino-3-phenyl-1-(4-quinazolin-4-yl-piperazin-1-yl)-propan-1-one(853678-27-0)

Safety Data

• Hazardous Substances Data: 853678-27-0(Hazardous Substances Data)

Upstream product

• 18942-49-9 Boc-D-Phe-OH 
• 59215-41-7 1-(4-quinazolinyl)piperazine 
• 209733-20-0 4-piperazinylquinazoline hydrochloride 
• 827598-29-8 4-(quinazolin-4-yl)piperazine-1-carboxylic acid tert-butyl ester 
• 5190-68-1 4-chloroquinazoline 

Relevant articles and documents

AKT PROTEIN KINASE INHIBITORS

The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.