854261-77-1

Basic information

• Product Name: benzyl 7-[1-(1-amidinophenyl-4-yl)-4-ethoxycarbonylpiperidin-4-ylmethoxy]-1,2,3,4-tetrahydroisoquinolin-2-carboxylate
• Synonyms: benzyl 7-[1-(1-amidinophenyl-4-yl)-4-ethoxycarbonylpiperidin-4-ylmethoxy]-1,2,3,4-tetrahydroisoquinolin-2-carboxylate
• CAS NO: 854261-77-1
• Molecular Weight: 570.689
• Mol File: 854261-77-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl 7-[1-(1-amidinophenyl-4-yl)-4-ethoxycarbonylpiperidin-4-ylmethoxy]-1,2,3,4-tetrahydroisoquinolin-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 7-[1-(1-amidinophenyl-4-yl)-4-ethoxycarbonylpiperidin-4-ylmethoxy]-1,2,3,4-tetrahydroisoquinolin-2-carboxylate(854261-77-1)
• EPA Substance Registry System: benzyl 7-[1-(1-amidinophenyl-4-yl)-4-ethoxycarbonylpiperidin-4-ylmethoxy]-1,2,3,4-tetrahydroisoquinolin-2-carboxylate(854261-77-1)

Safety Data

• Hazardous Substances Data: 854261-77-1(Hazardous Substances Data)

Upstream product

• 247132-47-4 7-(4-ethoxycarbonylpiperidin-4-ylmethoxy)-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid benzyl ester 
• 247132-46-3 benzyl 7-(1-tert-butoxycarbonyl-4-ethoxycarbonylpiperidin-4-ylmethoxy)-1,2,3,4-tetrahydroisoquinolin-2-carboxylate 
• 39989-39-4 7-methoxyisoquinoline 
• 1126-09-6 4-carbethoxypiperidine 
• 43207-78-9 7-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 1194-02-1 4-fluorobenzonitrile 
• 110192-19-3 7-hydroxy-1,2,3,4-tetrahydroisoquinoline hydrobromide 
• 142851-03-4 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate 
• 247132-40-7 7-hydroxy-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid benzyl ester 
• 247132-42-9 7-chloromethoxy-3,4-dihydro-1H-isoquinolin-2-carboxylate benzyl ester 
• 247132-41-8 benzyl 7-methylthiomethoxy-1,2,3,4-tetrahydroisoquinolin-2-carboxylate 

Relevant articles and documents

Synthesis and structure-activity relationships of novel selective factor Xa inhibitors with a tetrahydroisoquinoline ring

A series of novel 2,7-disubstituted tetrahydroisoquinoline derivatives were designed and synthesized. Among these derivatives, compounds 1 and 2 exhibited potent inhibitory activity against factor Xa (FXa) and good selectivity with respect to other serine