854666-04-9Relevant articles and documents
Chemoenzymatic Asymmetric Synthesis of 1,4-Benzoxazine Derivatives: Application in the Synthesis of a Levofloxacin Precursor
López-Iglesias, María,Busto, Eduardo,Gotor, Vicente,Gotor-Fernández, Vicente
, p. 3815 - 3824 (2015)
A versatile and general route has been developed for the asymmetric synthesis of a wide family of 3-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazines bearing different pattern substitutions in the aromatic ring. Whereas hydrolases were not suitable for resoluti