854777-89-2

Basic information

• Product Name: [4-chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone
• Synonyms: [4-chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone
• CAS NO: 854777-89-2
• Molecular Weight: 335.713
• Mol File: 854777-89-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: [4-chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: [4-chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone(854777-89-2)
• EPA Substance Registry System: [4-chloro-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone(854777-89-2)

Safety Data

• Hazardous Substances Data: 854777-89-2(Hazardous Substances Data)

Upstream product

• 854777-98-3 (4-hydroxy-8-trifluoromethyl-quinolin-3-yl)phenylmethanone 
• 31602-11-6 ethyl 4-chloro-8-(trifluoromethyl)quinoline-3-carboxylate 
• 591-51-5 phenyllithium 
• 88-17-5 2-(trifluoromethyl)benzenamine 
• 39973-76-7 ethyl 2-benzoyl-3-ethoxyacrylate 
• 854777-97-2 2-benzoyl-3-(2-trifluoromethylphenylamino)acrylic acid ethyl ester 

Downstream Products

• 854765-40-5 phenyl[4-phenyl(8-trifluoromethyl)quinolin-3-yl]methanone 
• 854766-06-6 (4-{[{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}(methyl)amino]methyl}phenyl)acetic acid 
• 854766-05-5 {4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid 
• 854778-03-3 methyl {4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetate 
• 854766-61-3 3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]benzaldehyde 
• 854765-99-4 [4-(3-aminophenyl)-8-(trifluoromethyl)quinolin-3-yl](phenyl)methanone 

Relevant articles and documents

Discovery of phenyl acetic acid substituted quinolines as novel liver X receptor agonists for the treatment of atherosclerosis

A structure-based approach was used to optimize our new class of quinoline LXR modulators leading to phenyl acetic acid substituted quinolines 15 and 16. Both compounds displayed good binding affinity for LXRβ and LXRα and were potent activators in LBD tr