855639-22-4Relevant articles and documents
Preparation of 2,3-dihydro-1H-spiro[isoquinoline-4,4′-piperidine] via an N-sulfonyl Pictet-Spengler reaction
Liu, Jian,Jian, Tianying,Sebhat, Iyassu,Nargund, Ravi
, p. 5115 - 5117 (2007/10/03)
A high yielding synthesis of variously substituted 2,3-dihydro-1H-spiro[isoquinoline-4,4′-piperidine] is reported. N-(2-nitrophenyl)sulfonyl was successfully used as both an activating and protecting group for the key Pictet-Spengler reaction.