856667-79-3 Usage
Description
Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methyl, ethyl ester is a complex organic chemical compound that belongs to the pyrrolo[2,1-f][1,2,4]triazine class. It is a methylated ethyl ester derivative, featuring a carboxylic acid group, an indazol-5-ylamino group, and a fluorophenylmethyl group. Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid,
4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methyl-, ethyl
ester may possess potential biological activities and is a promising candidate for research and development in the pharmaceutical industry, with its unique structure and properties.
Uses
Used in Pharmaceutical Research and Development:
Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methyl, ethyl ester is utilized as a chemical intermediate for the development of novel therapeutic agents. Its unique structure and potential biological activities make it a valuable compound for creating new drugs with specific targets and mechanisms of action.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methyl, ethyl ester serves as a key building block for the synthesis of various drug candidates. Its versatile chemical properties allow for the creation of diverse molecules with potential therapeutic applications.
Used in Drug Design:
Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methyl, ethyl ester is employed in drug design to create molecules with specific binding affinities and selectivity for targeted biological receptors. Its unique structural features can be exploited to develop drugs with improved efficacy and reduced side effects.
Used in Biochemical Research:
In biochemical research, Pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid, 4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methyl, ethyl ester can be used as a tool compound to study the interactions between small molecules and biological targets. This can provide valuable insights into the molecular mechanisms of diseases and the development of new therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 856667-79-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,6,6,6 and 7 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 856667-79:
(8*8)+(7*5)+(6*6)+(5*6)+(4*6)+(3*7)+(2*7)+(1*9)=233
233 % 10 = 3
So 856667-79-3 is a valid CAS Registry Number.
856667-79-3Relevant articles and documents
Hetero-aromatic compound and its use in medicine
-
, (2019/07/04)
The invention provides a hetero-aromatic compound or a stereisomer, geometric isomer, tautomer, despinner, nitrogen oxide, hydrate, solvate, metabolite, metabolism precursor and pharmaceutically acceptable salt or prodrug thereof, which is used for treating proliferative diseases. The invention also discloses a pharmaceutical composition containing the compound and an application of the compound or pharmaceutical composition thereof in preparation of a medicine for treating proliferative diseases.
Pyrrolotriazine-5-carboxylate ester inhibitors of EGFR and HER2 protein tyrosine kinases and a novel one-pot synthesis of C-4 subsitituted pyrrole-2,3-dicarboxylate diesters
Mastalerz, Harold,Gavai, Ashvinikumar V.,Fink, Brian,Struzynski, Charles,Tarrant, James,Vite, Gregory D.,Wong, Tai W.,Zhang, Guifen,Vyas, Dolatrai M.
, p. 528 - 533 (2007/10/03)
Pyrrolotriazines with an ester group at C-5 were prepared and evaluated as inhibitors of the EGFR and HER2 receptor tyrosine kinases, validated targets for cancer therapy. The C-5 ester (15) was at least as potent as its C-6 ester analogue (17), an exampl
