85692-37-1

Basic information

• Product Name: 1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE
• Synonyms: Ethanone, 1-(1-methyl-1H-imidazol-2-yl)- (9CI);ethanone, 1-(1-methyl-1H-imidazol-2-yl)-;2-Acetyl-1-MethyliMidazol...;2-Acetyl-1-MethyliMidazole;1-(1-Methyl-1H-iMidazol-2-yl)ethan-1-one;1-Methyl-2-acetylimidazole;1-(1-methyl-2-imidazolyl)ethanone;1-(1-methylimidazol-2-yl)ethanone
• CAS NO: 85692-37-1
• Molecular Formula: C₆H₈N₂O
• Molecular Weight: 124.14052
• Product Categories: ACETYLGROUP
• Mol File: 85692-37-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 105℃ (15 Torr)
• Appearance: /
• Density: 1.11±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 3.92±0.25(Predicted)
• CAS DataBase Reference: 1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE(85692-37-1)
• EPA Substance Registry System: 1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE(85692-37-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 85692-37-1(Hazardous Substances Data)

Usage

Description

1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE is a chemical compound with the molecular formula C6H9N2O. It is characterized by the presence of an imidazole ring and a methyl group, which contribute to its unique chemical properties and potential applications in various fields.

Uses

1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE is used as a chemical intermediate for the synthesis of various organic compounds and pharmaceuticals. Its unique structure allows it to act as a versatile building block in the development of new molecules with potential therapeutic or industrial applications.
Used in Research and Development:
1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE is used as a reagent in extensive ligand screening and mechanistic studies. Its ability to interact with various biological targets and its structural features make it a valuable tool for understanding the underlying mechanisms of chemical reactions and the development of new drugs.
Used in Pharmaceutical Industry:
1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE is used as a key component in the synthesis of pharmaceutical compounds. Its unique chemical properties enable it to be incorporated into drug molecules, potentially enhancing their efficacy, selectivity, and pharmacokinetic properties.
Used in Chemical Synthesis:
1-(1-METHYL-1H-IMIDAZOL-2-YL)-ETHANONE is used as a starting material for the synthesis of various organic compounds, including dyes, pigments, and other specialty chemicals. Its versatility and reactivity make it a valuable asset in the development of new chemical products.

Upstream product

• 53981-69-4 1-(1H-imidazol-2-yl)ethanone 
• 74-88-4 methyl iodide 

Downstream Products

• 127782-73-4 2-(1-methylethenyl)-1-methylimidazole 
• 118416-05-0 2-<3-(4-methylphenyl)acryloyl>-1-methyl-1H-imidazole 
• 199728-36-4 6-Methyl-2-(1-methyl-1H-imidazol-2-yl)-quinoline-4-carboxylic acid 
• 199728-34-2 2-(1-methyl-2-imidazolyl)quinoline-4-carboxylic acid 
• 199728-39-7 6-Bromo-2-(1-methyl-1H-imidazol-2-yl)-quinoline-4-carboxylic acid 
• 869789-69-5 (E)-3-(4-chlorophenyl)-1-(1-methyl-1H-imidazol-2-yl)prop-2-en-1-one 
• 860772-43-6 (E)-1-(1-methyl-1H-imidazole-2-yl)-3-phenylprop-2-en-1-one 
• 869789-68-4 (E)-3-(4-methoxyphenyl)-1-(1-methyl-1H-imidazol-2-yl)prop-2-en-1-one 
• 869789-73-1 (E)-3-(2-bromophenyl)-1-(1-methyl-1H-imidazol-2-yl)prop-2-en-1-one 
• 951291-07-9 ((2S,3S)-2-endo-3-phenylbicyclo[2.2.1]hept-5-en-2-yl)-(1-methyl-1H-imidazol-2-yl)methanone 

Relevant articles and documents

IMIDAZOLE-BASED ANTICANCER AGENTS AND DERIVATIVES THEREOF, AND METHODS OF MAKING AND USING SAME

Imidazole-based anticancer agents and derivatives thereof, as well as methods of making and methods of using the same, are described. The imidazole-based anticancer agents are HDAC inhibitor compounds having a 1-(1H-imidazol-2-yl)ethan-1-one or 1-(1H-imidazol-2-yl)ethane-1- thione moiety.