857283-93-3 Usage
General Description
4-(2-Methyl-1,3-thiazol-4-yl)benzoyl chloride is a chemical compound with the molecular formula C10H8ClNO. It is most commonly used in organic synthesis as a versatile acylating agent. The presence of the thiazole ring in the structure makes it useful in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. It is a colorless to light yellow liquid at room temperature, and it is highly reactive, particularly towards nucleophiles. Due to its reactivity and ability to form amides and esters, 4-(2-Methyl-1,3-thiazol-4-yl)benzoyl chloride is widely used in the pharmaceutical and agrochemical industries for the synthesis of various organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 857283-93-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,7,2,8 and 3 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 857283-93:
(8*8)+(7*5)+(6*7)+(5*2)+(4*8)+(3*3)+(2*9)+(1*3)=213
213 % 10 = 3
So 857283-93-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H8ClNOS/c1-7-13-10(6-15-7)8-2-4-9(5-3-8)11(12)14/h2-6H,1H3
857283-93-3Relevant articles and documents
Uncovering an allosteric mode of action for a selective inhibitor of human bloom syndrome protein
Chen, Xiangrong,Ali, Yusuf I.,Fisher, Charlotte EL,Arribas-Bosacoma, Raquel,Rajasekaran, Mohan B.,Williams, Gareth,Walker, Sarah,Booth, Jessica R.,Hudson, Jessica JR,Mark Roe,Pearl, Laurence H.,Ward, Simon E.,Pearl, Frances MG,Oliver, Antony W.
, (2021/04/02)
BLM (Bloom syndrome protein) is a RECQ-family helicase involved in the dissolution of complex DNA structures and repair intermediates. Synthetic lethality analysis implicates BLM as a promising target in a range of cancers with defects in the DNA damage r
