857951-83-8

Basic information

• Product Name: Acetamide, N-[4-[2-(acetyloxy)acetyl]phenyl]-
• CAS NO: 857951-83-8
• Molecular Formula: C12H13NO4
• Molecular Weight: 235.24
• Mol File: 857951-83-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetamide, N-[4-[2-(acetyloxy)acetyl]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[4-[2-(acetyloxy)acetyl]phenyl]-(857951-83-8)
• EPA Substance Registry System: Acetamide, N-[4-[2-(acetyloxy)acetyl]phenyl]-(857951-83-8)

Safety Data

• Hazardous Substances Data: 857951-83-8(Hazardous Substances Data)

Upstream product

• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 1260236-30-3 N-(1-(4-acetamidophenyl)vinyl)acetamide 
• 103-84-4 Acetanilid 
• 2719-21-3 4-(N-acetylamino)acetophenone 
• 127-09-3 sodium acetate 
• 21675-02-5 4-acetylaminophenacyl bromide 
• 140-49-8 N-[4-(chloroacetyl)phenyl]acetamide 
• 127-08-2 potassium acetate 

Downstream Products

• 1026261-22-2 2-(4-acetamidophenyl)-3-acetoxy-7,8-dimethylquinoline-4-carboxylic acid 
• 924899-54-7 C₁₈H₁₆N₂O₃ 
• 501696-51-1 4'-acetamido-2-hydroxyacetophenone 
• 72798-68-6 N-[4-(1⁽³⁾H-imidazol-4-yl)-phenyl]-acetamide 

Relevant articles and documents

PhI(OAc)2-promoted umpolung acetoxylation of enamides for the synthesis of α-acetoxy ketones

Umpolung is a fundamental concept in organic chemistry, which provides an alternative strategy for the synthesis of target compounds which were not easily accessible by conventional methods. Herein, a mild and efficient PhI(OAc)2-promoted umpolung acetoxylation reactions of enamides was developed for the synthesis of α-acetoxy ketones. The reaction tolerates a wide range of functional groups and affords α-acetoxy ketones in good to excellent yields. PhI(OAc)2 serves as a source of acetoxy in the reaction.