140-49-8 Usage
Description
4'-(Chloroacetyl)-acetanilide is an alpha-chloroketone derivative of acetanilide, where the para-position is substituted by a chloroacetyl group. It is an odorless yellow-orange solid or brown powder, which is a chemical compound with potential applications in various industries.
Uses
Used in Pharmaceutical Industry:
4'-(Chloroacetyl)-acetanilide is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be a key component in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Chemical Synthesis:
In the field of organic chemistry, 4'-(Chloroacetyl)-acetanilide serves as a versatile building block for the synthesis of a wide range of chemical products. Its reactivity and functional groups make it a valuable starting material for creating complex molecules with specific properties and applications.
Used in Research and Development:
4'-(Chloroacetyl)-acetanilide is also utilized in research and development laboratories for studying the properties and reactions of alpha-chloroketones. Its unique structure provides insights into the behavior of similar compounds and contributes to the advancement of chemical knowledge.
Used in Analytical Chemistry:
As an analytical reagent, 4'-(Chloroacetyl)-acetanilide can be employed in the detection and quantification of specific substances. Its chemical properties make it suitable for use in various analytical techniques, such as chromatography or spectroscopy, to identify and measure target compounds in complex samples.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
4'-(Chloroacetyl)-acetanilide reacts with oxidizers.
Fire Hazard
4'-(Chloroacetyl)-acetanilide is combustible.
Safety Profile
Moderately toxic by
ingestion. Mutation data reported. When
heated to decomposition it emits very toxic
fumes of Cland NOx. See also
CHLORIDES.
Check Digit Verification of cas no
The CAS Registry Mumber 140-49-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 140-49:
(5*1)+(4*4)+(3*0)+(2*4)+(1*9)=38
38 % 10 = 8
So 140-49-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H10ClNO2/c1-7(13)12-9-4-2-8(3-5-9)10(14)6-11/h2-5H,6H2,1H3,(H,12,13)
140-49-8Relevant articles and documents
Chlorination Reaction of Aromatic Compounds and Unsaturated Carbon-Carbon Bonds with Chlorine on Demand
Liu, Feng,Wu, Na,Cheng, Xu
supporting information, p. 3015 - 3020 (2021/05/05)
Chlorination with chlorine is straightforward, highly reactive, and versatile, but it has significant limitations. In this Letter, we introduce a protocol that could combine the efficiency of electrochemical transformation and the high reactivity of chlorine. By utilizing Cl3CCN as the chloride source, donating up to all three chloride atom, the reaction could generate and consume the chlorine in situ on demand to achieve the chlorination of aromatic compounds and electrodeficient alkenes.
Thiadiazinone derivatives
-
, (2008/06/13)
This invention provides thiadiazinone derivatives represented by the following formula (I) STR1 wherein R1 represents a hydrogen atom or C1 -C5 alkyl, R2 represents a 5- or 6-membered heterocyclic ring having (a) 1-3 nitrogen atoms, (b) a oxygen atom, (c) one sulfur atom, (d) 1-3 nitrogen atoms and one oxygen atom, or (e) 1-3 nitrogen atoms and one sulfur atom each of which rings may optionally be substituted by at least one substituent selected from the group consisting of C1 -C5 alkyl, cyano, hydroxy, C1 -C5 alkoxy, amino, C1 -C5 alkylamino, C2 -C6 dialkylamino, C2 -C5 acylamino, carboxyl, C2 -C5 alkoxycarbonyl and carbamoyl; or a pharmaceutically acceptable salt thereof. The compounds according to the present invention have an excellent cardiotonic activity, and are useful as active ingredients of a cardiotonic drug.