858614-87-6

Basic information

• Product Name: (3S,4S,5S)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4,5-epoxypiperidine
• Synonyms: (3S,4S,5S)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4,5-epoxypiperidine
• CAS NO: 858614-87-6
• Molecular Weight: 453.654
• Mol File: 858614-87-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (3S,4S,5S)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4,5-epoxypiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4S,5S)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4,5-epoxypiperidine(858614-87-6)
• EPA Substance Registry System: (3S,4S,5S)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4,5-epoxypiperidine(858614-87-6)

Safety Data

• Hazardous Substances Data: 858614-87-6(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 780782-29-8 tert-butyl (R)-3-hydroxy-3,6-dihydropyridine-1(2H)-carboxylate 
• 780782-21-0 (R)-N-tert-butoxycarbonyl-5-acetoxy-3-piperidene 
• 224779-27-5 tert-butyl 3-hydroxy-1,2,3,6-tetrahydropyridine-N-carboxylate 
• 224779-26-4 N-allyl-N-(2-hydroxy-but-3-enyl)-carbamic acid tert-butyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 804500-78-5 t-butyl (3R)-3-[(t-butyldiphenylsilyl)oxy]-3,6-dihydropyridine-1(2H)-carboxylate 

Downstream Products

• 858614-91-2 (3S,4S,5R)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4-hydroxy-5-vinylpiperidine 
• 858614-93-4 (3S,4S,5R)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4-hydroxy-5-methylpiperidine 
• 866923-70-8 (3S,4S,5R)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4-hydroxy-5-(hydroxymethyl)piperidine 
• 275363-98-9 (3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)piperidine 
• 866923-72-0 (3S,4S,5R)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4-hydroxy-5-(2-hydroxyethyl)piperidine 

Relevant articles and documents

Docking and SAR studies of D- and L-isofagomine isomers as human β-glucocerebrosidase inhibitors

We report the structure-activity relationship of a series of d-, and l-isofagomine and fagomine isomers as glycosidase inhibitors. Our study revealed that a positive charge at the anomeric position of d-isofagomines enhanced the potency toward β-glycosida

A short and concise synthesis of isofagomine, homoisofagomine, and 5′-deoxyisofagomine

A short and concise synthesis of isofagomine derivatives via the epoxidation of chiral N-Boc-5-hydroxy-3-piperidene, followed by regioselective epoxide ring opening is described. This constitutes the first reported synthesis of homoisofagomine and the 5′-