858647-47-9

Basic information

• Product Name: 2-methoxy-3-nitrophenyl N,N-diethylcarbamate
• Synonyms: 2-methoxy-3-nitrophenyl N,N-diethylcarbamate
• CAS NO: 858647-47-9
• Molecular Weight: 268.269
• Mol File: 858647-47-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methoxy-3-nitrophenyl N,N-diethylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methoxy-3-nitrophenyl N,N-diethylcarbamate(858647-47-9)
• EPA Substance Registry System: 2-methoxy-3-nitrophenyl N,N-diethylcarbamate(858647-47-9)

Safety Data

• Hazardous Substances Data: 858647-47-9(Hazardous Substances Data)

Upstream product

• 85630-19-9 N,N-diethyl-1-carbamyloxy-2-methoxybenzene 
• 858647-49-1 2-methoxy-3-nitro-6-(trimethylsilyl)phenyl N,N-diethylcarbamate 

Downstream Products

• 20734-71-8 2-methoxy-3-nitrophenol 

Relevant articles and documents

Directed ortho metalation-based methodology. Halo-, nitroso-, and boro-induced ipso-desilylation. Link to an in situ Suzuki reaction

(Chemical Equation Presented) Treatment of DoM-derived silylated aromatics 2-4 under standard electrophilic halogenation conditions cleanly affords ipso-desilyation products 5-7, while nitration of methoxy-substituted analogues 8, 9 leads to non-ipso isomers 10, 12 and 11, 13, controlled by a silicon steric effect. Sequential ipso-borodesilylation of 2a, 3a, and 20 followed by treatment with aryl halides under Pd-catalyzed conditions constitutes an in situ Suzuki-Miyaura cross-coupling protocol to biaryls and heterobiaryls 23.