859027-00-2Relevant articles and documents
THIENO (2, 3B) PYRAZINE COMPOUNDS AS B-RAF INHIBITORS
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, (2013/04/10)
The invention relates to compounds according to general Formula (I) or a pharmaceutically acceptable salt thereof. The compounds can be used for the treatment of cancer.
Synthesis, crystal structure, and spectral characterization of flumatinib mesylate
Xu, Gang,Shen, Hong,Tong, Taifeng,Lu, Aifeng,Gou, Shaohua
scheme or table, p. 2564 - 2570 (2010/09/30)
Flumatinib mesylate, a 3-substituted picolinamide derivative structurally similar to imatinib mesylate, was prepared. The compound was characterized by infrared, ultraviolet, NMR, and electrospray ionization-mass spectra together with X-ray crystal struct
Design and synthesis of 3-substituted benzamide derivatives as Bcr-Abl kinase inhibitors
Asaki, Tetsuo,Sugiyama, Yukiteru,Hamamoto, Taisuke,Higashioka, Masaya,Umehara, Masato,Naito, Haruna,Niwa, Tomoko
, p. 1421 - 1425 (2007/10/03)
A series of 3-substituted benzamide derivatives structurally related to STI-571 (imatinib mesylate), a Bcr-Abl tyrosine kinase inhibitor used to treat chronic myeloid leukemia (CML), was prepared and evaluated for antiproliferative activity against the Bc
