859217-05-3

Basic information

• Product Name: Bafetinib
• Synonyms: N-[3-([5,5'-Bipyrimidin]-2-ylamino)-4-methylphenyl]-4-[[(3S)-3-(dimethylamino)-1-pyrrolidinyl]methyl]-3-(trifluoromethyl)benzamide; N-{3-[([5,5'-bipyrimidin]-2-yl)amino]-4-methylphenyl}-4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]methyl}-3-(trifluoromethyl)benzamide
• CAS NO: 859217-05-3
• Molecular Formula: C₃₀H₃₁F₃N₈O
• Molecular Weight: 576.62
• Mol File: 859217-05-3.mol
• Article Data: 2

Chemical Properties

• Density: 1.36
• CAS DataBase Reference: Bafetinib(CAS DataBase Reference)
• NIST Chemistry Reference: Bafetinib(859217-05-3)
• EPA Substance Registry System: Bafetinib(859217-05-3)

Safety Data

• Hazardous Substances Data: 859217-05-3(Hazardous Substances Data)

Upstream product

• 859213-40-4 4-(bromomethyl)-3-trifluoromethyl-N-{4-methyl-3-[4-(5-pyrimidinyl)pyrimidin-2-ylamino]phenyl}benzamide 
• 261952-01-6 4-methyl-3-(trifluoromethyl)benzoic acid 
• 948553-14-8 4-(bromomethyl)-3-(trifluoromethyl)benzoyl chloride 
• 859213-39-1 4-(bromomethyl)-3-(trifluoromethyl)benzoic acid 

Relevant articles and documents

Design and synthesis of 3-substituted benzamide derivatives as Bcr-Abl kinase inhibitors

A series of 3-substituted benzamide derivatives structurally related to STI-571 (imatinib mesylate), a Bcr-Abl tyrosine kinase inhibitor used to treat chronic myeloid leukemia (CML), was prepared and evaluated for antiproliferative activity against the Bc