860640-13-7

Basic information

• Product Name: 2-Methyl-propane-2-sulfinic acid ((R)-3-[1,3]dioxan-2-yl-1-phenyl-propyl)-amide
• Synonyms: 2-Methyl-propane-2-sulfinic acid ((R)-3-[1,3]dioxan-2-yl-1-phenyl-propyl)-amide
• CAS NO: 860640-13-7
• Molecular Weight: 325.472
• Mol File: 860640-13-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Methyl-propane-2-sulfinic acid ((R)-3-[1,3]dioxan-2-yl-1-phenyl-propyl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-propane-2-sulfinic acid ((R)-3-[1,3]dioxan-2-yl-1-phenyl-propyl)-amide(860640-13-7)
• EPA Substance Registry System: 2-Methyl-propane-2-sulfinic acid ((R)-3-[1,3]dioxan-2-yl-1-phenyl-propyl)-amide(860640-13-7)

Safety Data

• Hazardous Substances Data: 860640-13-7(Hazardous Substances Data)

Upstream product

• 33884-43-4 2-(2-Bromoethyl)-1,3-dioxane 
• 186249-76-3 (R,E)-2-methyl-N-(phenylmethylene)-2-propanesulfinamide 

Downstream Products

• 860640-21-7 (R)-1-((S)-2-methyl-propane-2-sulfinyl)-2-phenyl-pyrrolidine 
• 860640-20-6 (R)-1-((R)-2-methyl-propane-2-sulfinyl)-2-phenyl-pyrrolidine 
• 196929-78-9 (R)-2-methylpropane-2-sulfinamide 
• 504-63-2 trimethyleneglycol 
• 56523-47-8 (R)-2-phenylpyrrolidine 
• 700-91-4 2-phenyl-1-pyrroline 

Relevant articles and documents

A rapid and general method for the asymmetric synthesis of 2-substituted pyrrolidines using tert-butanesulfinamide

A new method for the asymmetric synthesis of 2-substituted pyrrolidines in three steps from commercially available starting materials is described. Addition of the Grignard reagent prepared from 2-(2-bromoethyl)-1,3-dioxane to N-tert-butanesulfinyl aldimines proceeds in high yields and with good diastereoselectivities. The sulfinamide products are then cleanly converted into pyrrolidines in one step. The Royal Society of Chemistry 2005.