861136-88-1

Basic information

• Product Name: N-[3-(1-methoxy-3-methyl-5,6,7,8-tetrahydro-isoquinolin-4-ylamino)-phenyl]-acetamide
• Synonyms: N-[3-(1-methoxy-3-methyl-5,6,7,8-tetrahydro-isoquinolin-4-ylamino)-phenyl]-acetamide
• CAS NO: 861136-88-1
• Molecular Weight: 325.411
• Mol File: 861136-88-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-[3-(1-methoxy-3-methyl-5,6,7,8-tetrahydro-isoquinolin-4-ylamino)-phenyl]-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-(1-methoxy-3-methyl-5,6,7,8-tetrahydro-isoquinolin-4-ylamino)-phenyl]-acetamide(861136-88-1)
• EPA Substance Registry System: N-[3-(1-methoxy-3-methyl-5,6,7,8-tetrahydro-isoquinolin-4-ylamino)-phenyl]-acetamide(861136-88-1)

Safety Data

• Hazardous Substances Data: 861136-88-1(Hazardous Substances Data)

Upstream product

• 861136-82-5 4-bromo-3-methyl-5,6,7,8-tetrahydro-2H-isoquinolin-1-one 
• 861136-84-7 4-bromo-1-methoxy-3-methyl-5,6,7,8-tetrahydro-isoquinoline 
• 102-28-3 m-acetamide aniline 
• 14380-86-0 ethyl 2-(1,3-dioxoisoindolin-2-yl)propanoate 
• 37009-16-8 3-methyl-5,6,7,8-tetrahydro-2H-isoquinolin-1-one 
• 7114-80-9 3-methylisoquinolone 
• 5423-95-0 4-hydroxy-3-methyl-2H-isoquinolin-1-one 
• 85-44-9 phthalic anhydride 

Relevant articles and documents

Poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors based on a tetrahydro-1(2H)-isoquinolinone Scaffold: Synthesis, biological evaluation and X-ray crystal structure

The synthesis, activity and physical properties of two series of novel potent tetrahydro-1(2H)-isoquinolinone based PARP-1 inhibitors are described. The new structural classes with a non-planar ring system interact specifically with the PARP-1 protein at the nicotinamide-binding site. Georg Thieme Verlag Stuttgart.