86152-46-7

Basic information

• Product Name: 1H-1,2,4-Triazole-3-acetic acid, 5-amino-, ethyl ester
• CAS NO: 86152-46-7
• Molecular Formula: C6H10N4O2
• Molecular Weight: 170.171
• Mol File: 86152-46-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-1,2,4-Triazole-3-acetic acid, 5-amino-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,2,4-Triazole-3-acetic acid, 5-amino-, ethyl ester(86152-46-7)
• EPA Substance Registry System: 1H-1,2,4-Triazole-3-acetic acid, 5-amino-, ethyl ester(86152-46-7)

Safety Data

• Hazardous Substances Data: 86152-46-7(Hazardous Substances Data)

Usage

Description

1H-1,2,4-Triazole-3-acetic acid, 5-amino-, ethyl ester is a chemical compound with the molecular formula C6H8N4O2. It is a versatile building block in the pharmaceutical industry, known for its potential biological activities such as anti-inflammatory, anti-cancer, and anti-fungal properties.
Used in Pharmaceutical Industry:
1H-1,2,4-Triazole-3-acetic acid, 5-amino-, ethyl ester is used as a building block for the synthesis of various pharmaceutical compounds due to its versatile nature and potential therapeutic benefits.
Used in Drug Development and Research:
1H-1,2,4-Triazole-3-acetic acid, 5-amino-, ethyl ester is used as a valuable component in drug development and research for its potential biological activities, including anti-inflammatory, anti-cancer, and anti-fungal properties.

Upstream product

• 64-17-5 ethanol 
• 143832-52-4 2-(5-amino-1H-1,2,4-triazol-3-yl)acetic acid 
• 2318-25-4 ethyl 3-ethoxy-3-iminopropanoate hydrochloride 
• 2200-97-7 aminoguanidine hydrogencarbonate 

Downstream Products

• 1119566-67-4 ethyl 1-(4-bromobenzoyl)-5-amino-1H-1,2,4-triazole-3-acetate 
• 1119566-71-0 ethyl 1-(4-nitrobenzoyl)-5-amino-1H-1,2,4-triazole-3-acetate 
• 1119566-68-5 ethyl 1-(4-methoxybenzoyl)-5-amino-1H-1,2,4-triazole-3-acetate 
• 1119566-66-3 ethyl 1-(4-chlorobenzoyl)-5-amino-1H-1,2,4-triazole-3-acetate 
• 1119566-63-0 ethyl 1-benzoyl-5-amino-1H-1,2,4-triazole-3-acetate 

Relevant articles and documents

SYNTHESIS OF C-AZOYLACETIC ACID ESTERS BASED ON CARBETHOXYETHYLACETIMIDATE

Preparative methods were developed for synthesizing 1,2,4-triazolyl-1,3,4-oxadiazolyl-, 1,2,4-oxadiazolyl-, and 1,3,4-thiadiazolylacetic acid esters based on carbethoxyethylacetimidate chlorohydrate.

Design, synthesis and molecular modeling study of acylated 1,2,4-triazole-3-acetates with potential anti-inflammatory activity

The present investigation is concerned with the synthesis of different acylated 1,2,4-triazole-3-acetates with the objective of discovering novel and potent anti-inflammatory agents. Structures of the synthesized compounds were elucidated by spectral and

Synthesis and Some Transformations of 3-Substituted 1,2,4-Triazole-5-acetic Acids

The reaction of aminoguanidine hydrogen carbonate with malonic acid gave 5-amino-1,2,4-triazole-5-acetic acid whose further transformations resulted in azo and nitro 1,2,4-triazole derivatives containing carboxy and ethoxycarbonylmethyl groups at the ring carbon atom; their nitrosation afforded derivatives of 3-nitro-1,2,4-triazol-5-yl(hydroxyimino)acetic acid.