86215-40-9

Basic information

• Product Name: 1-(4-Bromo-phenyl)-3-azabicyclo[3.1.0]hexane
• Synonyms: 1-(4-Bromo-phenyl)-3-azabicyclo[3.1.0]hexane
• CAS NO: 86215-40-9
• Molecular Formula: C₁₁H₁₂BrN
• Molecular Weight: 238.12
• Mol File: 86215-40-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-Bromo-phenyl)-3-azabicyclo[3.1.0]hexane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Bromo-phenyl)-3-azabicyclo[3.1.0]hexane(86215-40-9)
• EPA Substance Registry System: 1-(4-Bromo-phenyl)-3-azabicyclo[3.1.0]hexane(86215-40-9)

Safety Data

• Hazardous Substances Data: 86215-40-9(Hazardous Substances Data)

Usage

Description

1-(4-Bromo-phenyl)-3-azabicyclo[3.1.0]hexane, also known as nBunce, is a chemical compound characterized by its bicyclic structure and the presence of a bromo-phenyl group. This unique structure and reactivity make it a valuable building block in the synthesis of various pharmaceuticals and organic compounds. It has been extensively studied for its potential applications in medicinal chemistry and drug development, particularly in the field of neuroscience. Moreover, it has shown promise as a molecular probe for investigating the function of specific brain receptors and neurotransmitters. However, due to its potential toxicity, it is crucial to handle and use 1-(4-Bromo-phenyl)-3-azabicyclo[3.1.0]hexane with proper safety precautions and under the guidance of trained professionals.

Uses

Used in Pharmaceutical Synthesis:
1-(4-Bromo-phenyl)-3-azabicyclo[3.1.0]hexane is used as a building block for the synthesis of various pharmaceuticals and organic compounds. Its unique structure and reactivity make it a valuable component in the development of new drugs and therapeutic agents.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(4-Bromo-phenyl)-3-azabicyclo[3.1.0]hexane is used as a key intermediate for the development of novel drug candidates. Its structural properties and reactivity contribute to the design and synthesis of potential therapeutic agents.
Used in Neuroscience Research:
1-(4-Bromo-phenyl)-3-azabicyclo[3.1.0]hexane is used as a molecular probe in neuroscience research. It aids in the study of the function of specific brain receptors and neurotransmitters, providing valuable insights into the underlying mechanisms of various neurological disorders.
Used in Drug Development:
In the realm of drug development, 1-(4-Bromo-phenyl)-3-azabicyclo[3.1.0]hexane is employed as a starting material for the creation of new pharmaceuticals. Its unique structural features and reactivity make it an essential component in the development of innovative treatments for various medical conditions.

Upstream product

• 66504-48-1 1-(p-Bromphenyl)-1,2-cyclopropan-dicarboximid 
• 41841-16-1 (4-bromo-phenyl)-acetic acid methyl ester 
• 77053-77-1 (1R,2S)-1-(4-Bromo-phenyl)-cyclopropane-1,2-dicarboxylic acid 
• 77053-66-8 (1R,2S)-1-(4-Bromo-phenyl)-cyclopropane-1,2-dicarboxylic acid dimethyl ester 
• 16532-79-9 4-Bromophenylacetonitrile 
• 1259556-21-2 1-(4-bromo-phenyl)-2-hydroxymethyl-cyclopropanecarbonitrile 

Downstream Products

• 863679-83-8 tert-butyl 1-(4-bromophenyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate 
• 1259555-01-5 1-(4-morpholin-4-yl-phenyl)-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester 
• 1259556-05-2 1-(4-morpholin-4-yl-phenyl)-3-(2,2,2-trifluoro-ethyl)-3-aza-bicyclo[3.1.0]hexane 
• 1259556-07-4 3-(2-methoxy-ethyl)-1-(4-morpholin-4-yl-phenyl)-3-aza-bicyclo[3.1.0]hexane 
• 1259556-54-1 1-(4-pyrrolidin-1-yl-phenyl)-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester 
• 1259556-55-2 1-[4-(3-fluoro-pyrrolidin-1-yl)-phenyl]-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester 
• 1259556-56-3 1-[4-(2-oxo-pyrrolidin-1-yl)-phenyl]-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester 
• 1259556-57-4 1-(4-thiomorpholin-4-yl-phenyl)-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester 
• 1259556-58-5 1-[4-(4-ethyl-5-oxo-[1,4]diazepan-1-yl)-phenyl]-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester 
• 1259556-25-6 1-(4-benzylamino-phenyl)-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester 
• 927812-93-9 tert-butyl 1-(4-aminophenyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate 
• 1259556-26-7 1-(4-benzyloxycarbonylamino-phenyl)-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester 
• 1259553-74-6 N-(3-{4-[3-(2-acetylamino-acetyl)-3-aza-bicyclo[3.1.0]hex-1-yl]-phenyl}-2-oxo-oxazolidin-(5S)-ylmethyl)-acetamide 
• 1259553-76-8 N-(2-(1-(4-((S)-5-(acetamidomethyl)-2-oxooxazolidin-3-yl)phenyl)-3-azabicyclo[3.1.0]hexan-3-yl)-2-oxoethyl)nicotinamide 

Relevant articles and documents

NOVEL AZABICYCLOHEXANES

The present invention relates to novel compounds of Formula I, their pharmaceutically acceptable derivatives, tautomeric forms, stereoisomers including R and S isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to processes for the synthesis of novel compounds of Formula I, their pharmaceutically acceptable derivatives, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof.