862791-44-4Relevant articles and documents
Structure-based design, synthesis, and biological evaluation of inhibitors of Mycobacterium tuberculosis type II dehydroquinase
Sánchez-Sixto, Cristina,Prazeres, Verónica F. V.,Castedo, Luis,Lamb, Heather,Hawkins, Alastair R.,González-Bello, Concepción
, p. 4871 - 4881 (2007/10/03)
The syntheses by Suzuki cross-coupling of 12 5-aryl analogues of the known inhibitor (LR,3/2,4R)-1,3,4-trihydroxycyclohex-5-en-1-carboxylic acid are reported. These compounds were found to be reversible competitive inhibitors against Mycobacterium tubercu