863647-61-4

Basic information

• Product Name: (4-{[4-methyl-2-(3-phenyl-propionylamino)-pentanoyl]-hydrazono}-butyl)-carbamic acid tert-butyl ester
• Synonyms: (4-{[4-methyl-2-(3-phenyl-propionylamino)-pentanoyl]-hydrazono}-butyl)-carbamic acid tert-butyl ester
• CAS NO: 863647-61-4
• Molecular Weight: 446.59
• Mol File: 863647-61-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-{[4-methyl-2-(3-phenyl-propionylamino)-pentanoyl]-hydrazono}-butyl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-{[4-methyl-2-(3-phenyl-propionylamino)-pentanoyl]-hydrazono}-butyl)-carbamic acid tert-butyl ester(863647-61-4)
• EPA Substance Registry System: (4-{[4-methyl-2-(3-phenyl-propionylamino)-pentanoyl]-hydrazono}-butyl)-carbamic acid tert-butyl ester(863647-61-4)

Safety Data

• Hazardous Substances Data: 863647-61-4(Hazardous Substances Data)

Upstream product

• 73286-71-2 N-(tert-butoxycarbonyl)-2,3-dihydropyrrole 
• 863647-64-7 N-(1-hydrazinocarbonyl-3-methyl-butyl)-3-phenyl-propionamide 
• 872143-47-0 (S)-4-Methyl-2-(3-phenyl-propionylamino)-pentanoic acid methyl ester 
• 75178-87-9 (4-hydroxybutyl)carbamic acid tert-butyl ester 

Downstream Products

• 685543-88-8 3-{N-(4-tert-butoxycarbonylamino-butyl)-N'-[4-methyl-2-(3-phenyl-propionylamino)-pentanoyl]-hydrazinocarbonyl}-acrylic acid ethyl ester 
• 863647-63-6 (4-{N'-[4-methyl-2-(3-phenyl-propionylamino)-pentanoyl]-hydrazino}-butyl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Aza-Peptide Michael Acceptors: A New Class of Inhibitors Specific for Caspases and Other Clan CD Cysteine Proteases

Aza-peptide Michael acceptors are a new class of irreversible inhibitors that are highly potent and specific for clan CD cysteine proteases. The aza-Asp derivatives were specific for caspases, while aza-Asn derivatives were effective legumain inhibitors. Aza-Lys and aza-Orn derivatives were potent inhibitors of gingipain K and clostripain. Aza-peptide Michael acceptors showed no cross reactivity toward papain, cathepsin B, and calpain.