86499-69-6

Basic information

• Product Name: (2-Oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-carbaMicacidtert-butylester
• Synonyms: (2-Oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-carbaMicacidtert-butylester;tert-Butyl (2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)carbaMate;tert-Butyl N-(2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl)carbamate
• CAS NO: 86499-69-6
• Molecular Formula: C₁₅H₂₀N₂O₃
• Molecular Weight: 276.3309
• Mol File: 86499-69-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 472.5±44.0 °C(Predicted)
• Appearance: /
• Density: 1.17±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 11.34±0.20(Predicted)
• CAS DataBase Reference: (2-Oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-carbaMicacidtert-butylester(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-carbaMicacidtert-butylester(86499-69-6)
• EPA Substance Registry System: (2-Oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-carbaMicacidtert-butylester(86499-69-6)

Safety Data

• Hazardous Substances Data: 86499-69-6(Hazardous Substances Data)

Usage

General Description

The chemical compound "(2-Oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-carbaMicacidtert-butylester" is a carbamic acid derivative with a tert-butyl ester group. It has a molecular formula of C15H19NO3 and a molar mass of 261.31 g/mol. (2-Oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-carbaMicacidtert-butylester belongs to the class of benzo[b]azepine derivatives and is commonly used in the pharmaceutical industry for its potential therapeutic applications. Its precise functions and uses may vary depending on its specific properties and the context in which it is applied, but it is generally recognized as an important chemical compound with pharmacological and biochemical relevance.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 86499-35-6 3-amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one 
• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 

Downstream Products

• 103825-24-7 3-amino-1-methyl-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one 
• 958075-42-8 tert-butyl [1-(3,5-difluorobenzyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]carbamate 
• 958075-56-4 tert-butyl (7-phenyl-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl)carbamate 
• 958075-57-5 3-amino-7-phenyl-1,3,4,5-tetrahydro-1-benzazapin-2-one hydrochloride 
• 958075-43-9 3-amino-1-(3,5-difluorobenzyl)-1,3,4,5-tetrahydro-1-benzazepin-2-one hydrochloride 
• 65028-92-4 2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-amine 

Relevant articles and documents

2-ALKOXY-3,4,5-TRIHYDROXY-ALKYLAMIDE-BENZAZEPINES, THE PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THE SAME

The present invention relates to 2-alkoxy-3,4,5-trihydroxyalkylamide benzodiazepine compounds, to pharmaceutical compositions comprising such compounds, to methods of treatment comprising administering such compounds, to processes for the preparation of such compounds, and to intermediate precursors to such compounds.

Lactam inhibitors of factor Xa and method

Lactam inhibitors are provided which have the structure including pharmaceutically acceptable salts thereof and all stereoisomers thereof, and prodrug esters thereof, wherein n is 1 to 5; and and R1, R2, R3, R4, R5 , R6, R7, R8, R9, R10, R10a, 1011 and R12 are as defined herein. These compounds are inhibitors of Factor Xa and thus are useful as anticoagulants. A method for treating cardiovascular diseases associated with thromboses is also provided.

3-Amino-(1)-benzazepin-2-one-1-alkanoic acids

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