86518-04-9

Basic information

• Product Name: Silanamine, 1-(1,1-dimethylethyl)-N,1,1-trimethyl-N-phenyl-
• CAS NO: 86518-04-9
• Molecular Formula: C13H23NSi
• Molecular Weight: 221.418
• Mol File: 86518-04-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Silanamine, 1-(1,1-dimethylethyl)-N,1,1-trimethyl-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Silanamine, 1-(1,1-dimethylethyl)-N,1,1-trimethyl-N-phenyl-(86518-04-9)
• EPA Substance Registry System: Silanamine, 1-(1,1-dimethylethyl)-N,1,1-trimethyl-N-phenyl-(86518-04-9)

Safety Data

• Hazardous Substances Data: 86518-04-9(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 100-61-8 N-methylaniline 
• 62-53-3 aniline 
• 53742-62-4 anilino(tert-butyldimethyl)silane 
• 74-88-4 methyl iodide 
• 1227476-15-4 Azobenzene 

Downstream Products

• 100-61-8 N-methylaniline 
• 2739-12-0 N-methylaniline hydrochloride 

Relevant articles and documents

Highly efficient chemoselective N-TBS protection of anilines under exceptional mild conditions in the eco-friendly solvent 2-methyltetrahydrofuran

A straightforward chemoselective protection of anilines as N-TBS derivatives is described by using a suitable deprotonation of the amine with methyllithium in the environmentally friendly and safer substitute of THF, 2-methyltetrahydrofuran, under exceptional mild reaction conditions (0 °C, 30 min). Interestingly, the protecting group maybe cleaved efficiently by simple treatment of N-TBS-anilines with silica gel in ethanol-water.

SELECTIVE N-MONOMETHYLATION OF PRIMARY AMINES via N-TRIALKYLSILYL-LITHIOAMINES

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