865471-09-6Relevant articles and documents
Ortho selectivity in SNAr substitutions of 2,4-dihaloaromatic compounds. Reactions with piperidine
Wendt, Michael D.,Kunzer, Aaron R.
supporting information; experimental part, p. 641 - 644 (2010/04/05)
A broad survey of aromatic compounds with halogens positioned both ortho and para to activating groups was studied in SNAr reactions with piperidine. Regioselectivities varied with the substituent group and the polarity of the solvent. Many act
1,4-Benzodiazepines as inhibitors of respiratory syncytial virus. The identification of a clinical candidate
Henderson, Elisa A.,Alber, Dagmar G.,Baxter, Robert C.,Bithell, Sian K.,Budworth, Joanna,Carter, Malcolm C.,Chubb, Ann,Cockerill, G. Stuart,Dowdell, Verity C. L.,Fraser, Ian J.,Harris, Robert A.,Keegan, Sally J.,Kelsey, Richard D.,Lumley, James A.,Stables, Jeremy N.,Weerasekera, Natasha,Wilson, Lara J.,Powell, Kenneth L.
, p. 1685 - 1692 (2008/02/01)
Respiratory syncytial virus (RSV) is the cause of one-fifth of all lower respiratory tract infections worldwide and is increasingly being recognized as representing a serious threat to patient groups with poorly functioning or immature immune systems. Rac