86552-35-4

Basic information

• Product Name: (4-phenylbutyl)-phosphinic acid,ethyl ester
• Synonyms: (4-phenylbutyl)-phosphinic acid,ethyl ester
• CAS NO: 86552-35-4
• Molecular Weight: 226.255
• Mol File: 86552-35-4.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (4-phenylbutyl)-phosphinic acid,ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-phenylbutyl)-phosphinic acid,ethyl ester(86552-35-4)
• EPA Substance Registry System: (4-phenylbutyl)-phosphinic acid,ethyl ester(86552-35-4)

Safety Data

• Hazardous Substances Data: 86552-35-4(Hazardous Substances Data)

Upstream product

• 14684-32-3 ethyl phosphinate 
• 768-56-9 4-Phenylbut-1-ene 
• 85672-92-0 (4-phenylbutyl)-phosphonous acid,diethyl ester 
• 78-10-4 tetraethoxy orthosilicate 
• 86552-32-1 (4-phenylbutyl)phosphinic acid 
• 64-17-5 ethanol 

Downstream Products

• 1071138-64-1 C₁₅H₂₇O₂PSi 
• 95986-16-6 ((E)-1-Hydroxy-but-2-enyl)-(4-phenyl-butyl)-phosphinic acid ethyl ester 
• 104902-85-4 4-[Ethoxy-(4-phenylbutyl)phosphinyl]-4,4-dimethyl-2-butanone 
• 104902-86-5 (3-Oxo-cyclopentyl)-(4-phenyl-butyl)-phosphinic acid ethyl ester 
• 106019-28-7 (4-phenylbutyl)phosphonic acid, diethyl ester 
• 95688-66-7 [Ethoxy-(4-phenylbutyl)phosphinyl]acetic acid, ethyl ester 
• 95986-07-5 3-[Ethoxy-(4-phenylbutyl)phosphinyl]propiononitrile 
• 95986-12-2 3-[Ethoxy-(4-phenylbutyl)phosphinyl]propionic acid, methyl ester 
• 95986-18-8 3-[Ethoxy-(4-phenyl-butyl)-phosphinoyl]-2-methyl-propionic acid methyl ester 
• 95986-08-6 3-[Ethoxy-(4-phenylbutyl)phosphinyl]propionic acid 
• 83623-46-5 [Ethoxy-(4-phenylbutyl)phosphinyl]acetic acid 
• 95688-70-3 [Ethoxy-(4-phenylbutyl)phosphinyl]propionic acid, ethyl ester 
• 95688-71-4 Bis-(4-phenyl-butyl)-phosphinic acid ethyl ester 
• 95688-69-0 3-[Ethoxy-(4-phenyl-butyl)-phosphinoyl]-propionic acid ethyl ester 

Relevant articles and documents

How Do Phosphinates React with Unactivated Alkenes Under Organic Photocatalyzed Conditions? Substrate Scope and Mechanistic Insights

The first visible-light-mediated, metal-free hydrophosphinylation of unactivated alkenes with ethyl and butyl phosphinates is described. The reaction works with a low catalyst loading of 9-mesityl-10-methylacridinium perchlorate (Fukuzumi photocatalyst, 0

Recent advances in phosphorus-carbon bond formation: Synthesis of H-phosphinic acid derivatives from hypophosphorous compounds

This account summarizes the research conducted in our laboratory over the past five years. New methodologies were devised for the formation of P-C bonds with a focus on the reactions of hypophosphorous acid derivatives. Three types of reactions have been developed: palladium-catalyzed cross-coupling, room-temperature radical addition, and palladium-catalyzed addition. Our results are summarized in each of these areas and include some of our most recent data. (1) Our palladium-catalyzed cross-coupling has been extended to the direct coupling of alkyl phosphinates with a variety of aryl, heteroaryl, and even alkenyl electrophiles. (2) The addition of sodium hypophosphite under radical conditions is extended from alkenes to alkynes. (3) The catalytic addition of hypophosphorous compounds using palladium catalysts (hydrophosphinylation) is also discussed.

Orthosilicate-mediated esterification of monosubstituted phosphinic acids

(matrix presented) Monosubstituted phosphinic acids are esterified with orthosilicates in excellent yields. Phosphinylidene-containing acids react selectively under these conditions, while disubstituted phosphinic acids and phosphonic acids remain unchanged. One-pot procedures are also described for the preparation of phosphinate esters from an alcohol. This novel method provides a convenient and general alternative to more commonly employed conditions such as diazomethane or carbodiimide.