866755-70-6

Basic information

• Product Name: (2R,3R,4R,5R)-2,5-Bis-((E)-3-bromo-allyloxy)-6-[N'-(4-tert-butyl-benzoyl)-hydrazino]-3,4-dihydroxy-6-oxo-hexanoic acid ((1S,2R)-2-hydroxy-indan-1-yl)-amide
• Synonyms: (2R,3R,4R,5R)-2,5-Bis-((E)-3-bromo-allyloxy)-6-[N'-(4-tert-butyl-benzoyl)-hydrazino]-3,4-dihydroxy-6-oxo-hexanoic acid ((1S,2R)-2-hydroxy-indan-1-yl)-amide
• CAS NO: 866755-70-6
• Molecular Weight: 753.485
• Mol File: 866755-70-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R,4R,5R)-2,5-Bis-((E)-3-bromo-allyloxy)-6-[N'-(4-tert-butyl-benzoyl)-hydrazino]-3,4-dihydroxy-6-oxo-hexanoic acid ((1S,2R)-2-hydroxy-indan-1-yl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4R,5R)-2,5-Bis-((E)-3-bromo-allyloxy)-6-[N'-(4-tert-butyl-benzoyl)-hydrazino]-3,4-dihydroxy-6-oxo-hexanoic acid ((1S,2R)-2-hydroxy-indan-1-yl)-amide(866755-70-6)
• EPA Substance Registry System: (2R,3R,4R,5R)-2,5-Bis-((E)-3-bromo-allyloxy)-6-[N'-(4-tert-butyl-benzoyl)-hydrazino]-3,4-dihydroxy-6-oxo-hexanoic acid ((1S,2R)-2-hydroxy-indan-1-yl)-amide(866755-70-6)

Safety Data

• Hazardous Substances Data: 866755-70-6(Hazardous Substances Data)

Upstream product

• 652993-21-0 2,5-O-bis((2E)-3-bromo-2-propen-1-yl)-L-mannaro-1,4:3,6-di-γ-lactone 
• 7480-35-5 (1S,2R)-1-amino-2-indanol 
• 866755-90-0 (2R)-2-[(2E)-3-bromo-2-propenyloxy]-2-{(2R,3R,4R)-4-[(2E)-3-bromo-2-propenyloxy]-3-hydroxy-5-oxo-tetrahydrofuran-2-yl}-1N-(2-hydroxyindan-1-yl)ethanamide 
• 43100-38-5 4-tert-butylbenzoic acid hydrazide 

Relevant articles and documents

Synthesis of malarial plasmepsin inhibitors and prediction of binding modes by molecular dynamics simulations

A series of inhibitors of the malarial aspartic proteases Plm I and II have been synthesized with L-mannitol as precursor. These inhibitors are characterized by either a diacylhydrazine or a five-membered oxadiazole ring replacing backbone amide functiona