867331-09-7

Basic information

• Product Name: Phenol, 3-(3-amino-5-methyl-1,2,4-benzotriazin-7-yl)-4-chloro-
• CAS NO: 867331-09-7
• Molecular Formula: C14H11ClN4O
• Molecular Weight: 286.721
• Mol File: 867331-09-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Phenol, 3-(3-amino-5-methyl-1,2,4-benzotriazin-7-yl)-4-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 3-(3-amino-5-methyl-1,2,4-benzotriazin-7-yl)-4-chloro-(867331-09-7)
• EPA Substance Registry System: Phenol, 3-(3-amino-5-methyl-1,2,4-benzotriazin-7-yl)-4-chloro-(867331-09-7)

Safety Data

• Hazardous Substances Data: 867331-09-7(Hazardous Substances Data)

Upstream product

• 867330-72-1 7-(2-chloro-5-methoxyphenyl)-5-methyl-1,2,4-benzotriazine-3-ylamine 
• 867330-26-5 7-bromo-5-methyl-1,2,4-benzotriazin-3-ylamine 
• 913835-71-9 (2-chloro-5-hydroxy-phenyl)boronic acid 
• 77811-44-0 4-bromo-2-methyl-6-nitroaniline 
• 677297-87-9 7-bromo-5-methylbenzo[1,2,4]triazin-3-ylamine 1-oxide 

Downstream Products

• 867334-05-2 avastin 

Relevant articles and documents

The design and preliminary structure-activity relationship studies of benzotriazines as potent inhibitors of Abl and Abl-T315I enzymes

We describe the design, synthesis and structure-activity relationship studies in optimizing a series of benzotriazine compounds as potent inhibitors of both Abl and Abl-T315I enzymes. The design includes targeting of an acid functional residue on the αC-h

Benzotriazine inhibitors of kinases

The invention provides benzotriazine compounds having formula (I). The benzotriazine compounds of the invention are capable of inhibiting kinases, such members of the Src kinase family, and various other specific receptor and non-receptor kinases.