869101-42-8

Basic information

• Product Name: {(S)-3-[2-Bromo-eth-(Z)-ylidene]-4-methylene-cyclohexyloxy}-tert-butyl-dimethyl-silane
• Synonyms: {(S)-3-[2-Bromo-eth-(Z)-ylidene]-4-methylene-cyclohexyloxy}-tert-butyl-dimethyl-silane
• CAS NO: 869101-42-8
• Molecular Weight: 331.368
• Mol File: 869101-42-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(S)-3-[2-Bromo-eth-(Z)-ylidene]-4-methylene-cyclohexyloxy}-tert-butyl-dimethyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: {(S)-3-[2-Bromo-eth-(Z)-ylidene]-4-methylene-cyclohexyloxy}-tert-butyl-dimethyl-silane(869101-42-8)
• EPA Substance Registry System: {(S)-3-[2-Bromo-eth-(Z)-ylidene]-4-methylene-cyclohexyloxy}-tert-butyl-dimethyl-silane(869101-42-8)

Safety Data

• Hazardous Substances Data: 869101-42-8(Hazardous Substances Data)

Upstream product

• 96685-53-9 (2Z)-2-<(5S)-5-(tert-butyldimethylsilyloxy)-2-methylene-cyclohexylidene>-ethanol 

Downstream Products

• 869101-32-6 (1R,3aR,4S,5S,7aR)-4-Allyl-5-{2-[(S)-5-(tert-butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-ethyl}-1-((R)-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-ol 
• 869101-43-9 {(S)-3-[2-[(1R,3aR,4S,5S,7aR)-4-Allyl-1-((R)-1,5-dimethyl-hexyl)-4-methoxy-7a-methyl-octahydro-inden-5-yl]-eth-(Z)-ylidene]-4-methylene-cyclohexyloxy}-tert-butyl-dimethyl-silane 
• 869101-36-0 (1R,3aR,5S,7aR)-5-{2-[(S)-5-(tert-Butyl-dimethyl-silanyloxy)-2-methylene-cyclohex-(Z)-ylidene]-ethyl}-1-((R)-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-one 

Relevant articles and documents

RCM for the construction of novel steroid-like polycyclic systems. 1. Studies on the synthesis of a PreD3-D3 transition state analogue

Natural and nonnatural polycyclic systems containing eight-membered carbocycles constitute a large class of compounds of importance in organic chemistry, biology, and medicine. Here we describe a new strategy by which complex polycyclic steroid-like systems can be constructed on the steroid CD framework, by a combination of RCM and Heck cyclizations. The method is exemplified by its application to the stereoselective synthesis of 6-8-6 fused carbocyclic systems that mimic the putative transition structure of the isomerization of previtamin D3 to vitamin D3.