869725-56-4 Usage
General Description
2-bromo-5-(trifluoromethyl)-benzenepropanoic acid is an organic compound with the chemical formula C10H8BrF3O2. It is a derivative of benzenepropanoic acid, with a bromine atom and a trifluoromethyl group attached to the benzene ring. 2-bromo-5-(trifluoromethyl)-benzenepropanoic acid has applications in organic synthesis and pharmaceuticals, and it is used as a building block in the production of other organic compounds. It is a white solid at room temperature and is sparingly soluble in water but more soluble in organic solvents such as ethanol and ethyl acetate. Its chemical properties make it suitable for a variety of reactions and processes in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 869725-56-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,7,2 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 869725-56:
(8*8)+(7*6)+(6*9)+(5*7)+(4*2)+(3*5)+(2*5)+(1*6)=234
234 % 10 = 4
So 869725-56-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H8BrF3O2/c11-8-3-2-7(10(12,13)14)5-6(8)1-4-9(15)16/h2-3,5H,1,4H2,(H,15,16)
869725-56-4Relevant articles and documents
Discovery of INCB9471, a potent, selective, and orally bioavailable CCR5 antagonist with potent anti-HIV-1 activity
Xue, Chu-Biao,Chen, Lihua,Cao, Ganfeng,Zhang, Ke,Wang, Anlai,Meloni, David,Glenn, Joseph,Anand, Rajan,Xia, Michael,Kong, Ling,Huang, Taisheng,Feng, Hao,Zheng, Changsheng,Li, Mei,Galya, Laurine,Zhou, Jiacheng,Shin, Niu,Baribaud, Fredric,Solomon, Kim,Scherle, Peggy,Zhao, Bitao,Diamond, Sharon,Emm, Tom,Keller, Douglas,Contel, Nancy,Yeleswaram, Swamy,Vaddi, Kris,Hollis, Gregory,Newton, Robert,Friedman, Steven,Metcalf, Brian
, p. 483 - 487 (2011/03/20)
To identify a CCR5 antagonist as an HIV-1 entry inhibitor, we designed a novel series of indane derivatives based on conformational considerations. Modification on the indane ring led to the discovery of compound 22a (INCB9471) that exhibited high affinit
