870007-79-7

Basic information

• Product Name: 2-[4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone hydrochloride
• Synonyms: 2-[4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone hydrochloride;Ethanone, 2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-diMethylethyl)-2-ethoxyphenyl]-4,5-dihydro-1H-iMidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-Morpholinyl)-, hydrochloride (1:1);2-[4-[(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-1-yl]-1-morpholin-4-ylethanone:hydrochloride
• CAS NO: 870007-79-7
• Molecular Formula: C38H45Cl2N5O4.ClH
• Molecular Weight: 743.171
• Mol File: 870007-79-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 790.7 °C at 760 mmHg
• Flash Point: 432 °C
• Appearance: /
• Vapor Pressure: 5.6E-25mmHg at 25°C
• CAS DataBase Reference: 2-[4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone hydrochloride(870007-79-7)
• EPA Substance Registry System: 2-[4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone hydrochloride(870007-79-7)

Safety Data

• Hazardous Substances Data: 870007-79-7(Hazardous Substances Data)

Usage

Composition

Piperazinyl derivative with a hydrochloride moiety

Potential Activities

Antidepressant: Possesses properties that may alleviate symptoms of depression.
Anxiolytic: Shows potential in reducing anxiety levels.
Antiemetic: Potential to mitigate nausea and vomiting.

Mechanism of Action

Selective Serotonin Reuptake Inhibitor (SSRI): Targets serotonin transporter, hindering serotonin reuptake.
Action on Neurotransmitter Systems: Influences various neurotransmitter systems, leading to diverse therapeutic effects.

Therapeutic Uses

Anxiety Disorders: Potential treatment for anxiety-related conditions.
Depression: May aid in alleviating symptoms of depression.
Nausea: Potential application in managing nausea.

Specific Affinity

Serotonin 5-HT2 Receptor: Exhibits selectivity and affinity towards the serotonin 5-HT2 receptor.

InChI:InChI=1/C38H45Cl2N5O4.ClH/c1-5-49-32-24-28(38(2,3)4)10-15-31(32)36-41-34(26-6-11-29(39)12-7-26)35(27-8-13-30(40)14-9-27)45(36)37(47)44-18-16-42(17-19-44)25-33(46)43-20-22-48-23-21-43;/h6-15,24,34-35H,5,16-23,25H2,1-4H3;1H/t34-,35+;/m0./s1

Upstream product

• 870007-53-7 (4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dihydro-1H-imidazole 

Relevant articles and documents

NOVEL CIS-IMIDAZOLINES

Formula (I) and the pharmaceutically acceptable salts and esters thereof, wherein X1, X2, X3,Y1, Y2 and R are described herein inhibit the interaction of MDM2 protein with a p53-like peptide and hence have anti proiferative activity.