870122-74-0 Usage
Description
(E)-1-(2-bromovinyl)-4-fluorobenzene is a halogenated aromatic chemical compound with the molecular formula C8H6BrF. It features a fluoro group and a bromovinyl group, which means it has both fluorine and bromine atoms bonded to a benzene ring. This unique chemical structure endows it with potential applications in various fields, including organic synthesis, chemical research, pharmaceuticals, and agrochemicals.
Uses
Used in Organic Synthesis:
(E)-1-(2-bromovinyl)-4-fluorobenzene is used as a building block in organic synthesis for creating a variety of complex organic molecules. Its unique combination of fluorine and bromine atoms allows for specific reactivity patterns that can be exploited in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Chemical Research:
In the field of chemical research, (E)-1-(2-bromovinyl)-4-fluorobenzene serves as a model compound for studying the effects of halogen substitution on aromatic systems. It can be used to investigate reaction mechanisms, understand the influence of electron-withdrawing and electron-donating groups, and explore the impact of steric effects on chemical reactivity.
Used in Pharmaceutical Development:
(E)-1-(2-bromovinyl)-4-fluorobenzene is used as a key intermediate in the development of pharmaceuticals. Its unique structure may offer advantages in the design of new drugs, potentially leading to improved pharmacokinetic properties, such as enhanced solubility, bioavailability, or targeted delivery.
Used in Agrochemicals:
In the agrochemical industry, (E)-1-(2-bromovinyl)-4-fluorobenzene may be utilized as a starting material for the synthesis of novel pesticides or herbicides. Its halogenated nature could provide the necessary properties for these applications, such as increased stability, selectivity, or efficacy against target pests.
Check Digit Verification of cas no
The CAS Registry Mumber 870122-74-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,0,1,2 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 870122-74:
(8*8)+(7*7)+(6*0)+(5*1)+(4*2)+(3*2)+(2*7)+(1*4)=150
150 % 10 = 0
So 870122-74-0 is a valid CAS Registry Number.
870122-74-0Relevant articles and documents
Selective Rhodium-Catalyzed Hydroformylation of Terminal Arylalkynes and Conjugated Enynes to (Poly)enals Enabled by a π-Acceptor Biphosphoramidite Ligand
Zhao, Jiangui,Zheng, Xueli,Tao, Shaokun,Zhu, Yuxin,Yi, Jiwei,Tang, Songbai,Li, Ruixiang,Chen, Hua,Fu, Haiyan,Yuan, Maolin
supporting information, p. 6067 - 6072 (2021/08/16)
The hydroformylation of terminal arylalkynes and enynes offers a straightforward synthetic route to the valuable (poly)enals. However, the hydroformylation of terminal alkynes has remained a long-standing challenge. Herein, an efficient and selective Rh-catalyzed hydroformylation of terminal arylalkynes and conjugated enynes has been achieved by using a new stable biphosphoramidite ligand with strong π-acceptor capacity, which affords various important E-(poly)enals in good yields with excellent chemo- and regioselectivity at low temperatures and low syngas pressures.
Construction of Phenanthrenes and Chrysenes from β-Bromovinylarenes via Aryne Diels-Alder Reaction/Aromatization
Singh, Vikram,Verma, Ram Subhawan,Khatana, Anil K.,Tiwari, Bhoopendra
supporting information, p. 14161 - 14167 (2019/10/28)
A highly efficient transition-metal-free general method for the synthesis of polycyclic aromatic hydrocarbons like phenanthrenes and chrysenes (and tetraphene) from β-bromovinylarenes and arynes has been developed. The reactions proceed via an aryne Diels-Alder (ADA) reaction, followed by a facile aromatization. This is the first report on direct construction of chrysenes (and tetraphene) using the ADA approach. Unlike the literature method which is limited to only 9/10-substituted derivatives, this method gives access to a wide variety of functionalized phenanthrenes.
Ni-catalyzed reductive coupling of α-halocarbonyl derivatives with vinyl bromides
Qiu, Canbin,Yao, Ken,Zhang, Xinghua,Gong, Hegui
supporting information, p. 11332 - 11335 (2016/12/18)
This work describes the vinylation of α-halo carbonyl compounds with vinyl bromides under Ni-catalyzed reductive coupling conditions. While aryl-conjugated vinyl bromides entail pyridine as the sole labile ligand, the alkyl-substituted vinyl bromides require both bipyridine and pyridine as the co-ligands.
