870679-49-5Relevant articles and documents
A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2′,4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-Tetrahydrobenzo[6,7]cyclohepta[1,2-c ]pyrazole-3-carboxamide and analogue derivatives
Lazzari, Paolo,Distinto, Rita,Manca, Ilaria,Baillie, Gemma,Murineddu, Gabriele,Pira, Marilena,Falzoi, Matteo,Sani, Monica,Morales, Paula,Ross, Ruth,Zanda, Matteo,Jagerovic, Nadine,Pinna, Gérard Aimè
, p. 194 - 208 (2016/06/09)
8-Chloro-1-(2′,4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-Tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide 9a was discovered as potent and selective CB1 antagonist by part of our group few years ago. In particular it was reported to
PHARMACEUTICAL COMPOSITIONS
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Page/Page column 29, (2010/09/05)
Microemulsions of pharmaceutical compositions comprising, the following components (% by weight), the sum of the components being 100%: S) from 0.01 to 95% of one or more compounds selected from surfactants, polymers, forming organized structures as: aggr
Tricyclic pyrazoles. 3. Synthesis, biological evaluation, and molecular modeling of analogues of the cannabinoid antagonist 8-chloro-1-(2′, 4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7] cyclohepta[1,2-c]pyrazole-3-carboxamide
Murineddu, Gabriele,Ruiu, Stefania,Loriga, Giovanni,Manca, Ilaria,Lazzari, Paolo,Reali, Roberta,Pani, Luca,Toma, Lucio,Pinna, Gérard A.
, p. 7351 - 7362 (2007/10/03)
A series of analogues of 8-chloro-1-(2′,4′-dichlorophenyl)-AT- piperidin-1-yl-1,4,5,6-tetrahydrobenzo-[6,7]cyclohepta[1,2-c] pyrazole-3-carboxamide 4a (NESS 0327) (Ruiu, S.; Pinna, G. A.; Marchese, G.; Mussinu, J. M.; Saba, P.; Tambaro, S.; Casti, P.; Var