95207-68-4

Basic information

• Product Name: 3-AMINO-6,7,8,9-TETRAHYDRO-5H-BENZO[7]ANNULEN-5-ONE
• Synonyms: 3-AMINO-6,7,8,9-TETRAHYDRO-5H-BENZO[7]ANNULEN-5-ONE
• CAS NO: 95207-68-4
• Molecular Formula: C₁₁H₁₃NO
• Molecular Weight: 175.23
• Mol File: 95207-68-4.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-AMINO-6,7,8,9-TETRAHYDRO-5H-BENZO[7]ANNULEN-5-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-6,7,8,9-TETRAHYDRO-5H-BENZO[7]ANNULEN-5-ONE(95207-68-4)
• EPA Substance Registry System: 3-AMINO-6,7,8,9-TETRAHYDRO-5H-BENZO[7]ANNULEN-5-ONE(95207-68-4)

Safety Data

• Hazardous Substances Data: 95207-68-4(Hazardous Substances Data)

Usage

General Description

3-AMINO-6,7,8,9-TETRAHYDRO-5H-BENZO[7]ANNULEN-5-ONE is a chemical compound with the molecular formula C13H13NO. It is a heterocyclic compound that belongs to the class of benzannulenes, which are polycyclic aromatic hydrocarbons. The compound contains an aminomethyl group and a carbonyl group, and it is in the form of a tetrahydrobenzo[7]annulene ring system. It has potential applications in organic synthesis, medicinal chemistry, and material science due to its unique structure and reactivity. Additionally, it may have biological activity and could be of interest for further research in drug discovery and development.

Upstream product

• 7507-93-9 3-nitro-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one 
• 826-73-3 1-Benzosuberone 

Downstream Products

• 21413-77-4 3-chloro-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one 
• 870679-45-1 9-chloro-1-(2′,4′-dichlorophenyl)-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxylic acid 
• 870679-49-5 ethyl 9-chloro-1-(2′,4′-dichlorophenyl)-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxylate 
• 740842-30-2 (9-oxo-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl) carbamic acid benzyl ester 
• 740842-31-3 [N-5-hydroxy(1,2,3,4,5-pentahydrobenzo[a][7]annulene-7-yl) (phenylmethoxy) carboxamide], 
• 5454-03-5 3-hydroxy-6,7,8,9-tetrahydro-5H-benzo(a)cyclohepten-5-one 
• 35872-55-0 3-Benzyloxy-6,7,8,9-tetrahydrobenzocyclohepten-5-one 

Relevant articles and documents

Vinyl Carbocations Generated under Basic Conditions and Their Intramolecular C-H Insertion Reactions

Here we report the surprising discovery that high-energy vinyl carbocations can be generated under strongly basic conditions, and that they engage in intramolecular sp3 C-H insertion reactions through the catalysis of weakly coordinating anion salts. This approach relies on the unconventional combination of lithium hexamethyldisilazide base and the commercially available catalyst, triphenylmethylium tetrakis(pentafluorophenyl)borate. These reagents form a catalytically active lithium species that enables the application of vinyl cation C-H insertion reactions to heteroatom-containing substrates.

Benzimidazolone bioisosteres of potent GluN2B selective NMDA receptor antagonists

Overactivation of the NMDA receptor is associated with excitotoxic events leading to neurodegenerative processes as observed during the development of Alzheimer's disease, ParFnson's disease, Chorea Huntington and epilepsy. Negative allosteric modulators

REACTIVE LABELLING COMPOUNDS AND USES THEREOF

Provided are azido-BODIPY compounds of formula (I), cyclooctyne-based fluorogenic probes of formula (IV), and activity-based probes of formula (VI). These compounds undergo azide alkyne cycloadditions (AAC) with to form triazolyl products. The provided compounds are useful for detection and imaging of alkyne-, or azide-containing molecules. Methods for detection and imaging biomolecules using compounds of the present disclosure are disclosed.