871819-39-5 Usage
General Description
1H-Pyrrole-2-acetic acid, 3-(methoxycarbonyl)-1-methyl-, methyl ester is a chemical compound with the molecular formula C11H13NO3. It is a methyl ester derivative of 1H-pyrrole-2-acetic acid, which is a pyrrole derivative and an important building block in medicinal chemistry. The methoxycarbonyl group is a protective group commonly used in organic synthesis to protect reactive functional groups. 1H-Pyrrole-2-acetic acid, 3-(methoxycarbonyl)-1-methyl-, methyl ester may have potential applications in pharmaceuticals and organic synthesis due to its structural features and reactivity. It is important to handle this chemical with care and follow all safety protocols when working with it in the laboratory.
Check Digit Verification of cas no
The CAS Registry Mumber 871819-39-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,1,8,1 and 9 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 871819-39:
(8*8)+(7*7)+(6*1)+(5*8)+(4*1)+(3*9)+(2*3)+(1*9)=205
205 % 10 = 5
So 871819-39-5 is a valid CAS Registry Number.
871819-39-5Relevant articles and documents
Discovery of 1-[4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin- 7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a brain penetrant 5-azaindole CB2 agonist for the treatment of chronic pain
Giblin, Gerard M. P.,Billinton, Andrew,Briggs, Michael,Brown, Andrew J.,Chessell, Iain P.,Clayton, Nick M.,Eatherton, Andrew J.,Goldsmith, Paul,Haslam, Carl,Johnson, Matthew R.,Mitchell, William L.,Naylor, Alan,Perboni, Alcide,Slingsby, Brian P.,Wilson, Alex W.
supporting information; experimental part, p. 5785 - 5788 (2010/02/28)
We report the synthesis and SAR of a series of novel azaindole CB 2 agonists. 6-Azaindole 18 showed activity in an acute pain model but was inactive in a chronic model. 18 is a Pgp substrate with low brain penetration. The template was redesign
PYRROLOPYRIDINE DERIVATIVES
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, (2008/06/13)
The present invention relates to novel pyrrolopyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.
