871819-42-0

Basic information

• Product Name: 1H-Pyrrolo[3,2-c]pyridine-7-carboxylic acid, 4,5-dihydro-1-Methyl-4-oxo-, Methyl ester
• Synonyms: 1H-Pyrrolo[3,2-c]pyridine-7-carboxylic acid, 4,5-dihydro-1-Methyl-4-oxo-, Methyl ester;methyl 1-methyl-4-oxo-1H,4H,5H-pyrrolo[3,2-c]pyridine-7-carboxylate;Methyl 4,5-dihydro-1-methyl-4-oxo-1H-pyrrolo[3,2-c]pyridine-7-carboxylate
• CAS NO: 871819-42-0
• Molecular Formula: C10H10N2O3
• Molecular Weight: 206.198
• Mol File: 871819-42-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrrolo[3,2-c]pyridine-7-carboxylic acid, 4,5-dihydro-1-Methyl-4-oxo-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[3,2-c]pyridine-7-carboxylic acid, 4,5-dihydro-1-Methyl-4-oxo-, Methyl ester(871819-42-0)
• EPA Substance Registry System: 1H-Pyrrolo[3,2-c]pyridine-7-carboxylic acid, 4,5-dihydro-1-Methyl-4-oxo-, Methyl ester(871819-42-0)

Safety Data

• Hazardous Substances Data: 871819-42-0(Hazardous Substances Data)

Usage

General Description

1H-Pyrrolo[3,2-c]pyridine-7-carboxylic acid, 4,5-dihydro-1-Methyl-4-oxo-, Methyl ester is a chemical compound with potential pharmaceutical applications. It is a methyl ester derivative of pyrrolopyridine carboxylic acid, which is known for its potential as an anti-cancer and anti-inflammatory agent. 1H-Pyrrolo[3,2-c]pyridine-7-carboxylic acid, 4,5-dihydro-1-Methyl-4-oxo-, Methyl ester may possess similar properties, making it a potential candidate for drug development. Its chemical structure and properties may make it suitable for further research and testing in the development of novel therapeutic agents for various medical conditions.

Upstream product

• 871819-41-9 methyl 2-{(Z)-2-amino-1-[(rnethyloxy)carbonyl]ethenyl}-1-methyl-1H-pyrrole-3-carboxylate 
• 925917-48-2 2-(2-amino-1-methoxycarbonyl-vinyl)-1-methyl-1H-pyrrole-3-carboxylic acid methyl ester 
• 871819-40-8 2-(2-hydroxy-1-methoxycarbonyl-vinyl)-1-methyl-1H-pyrrole-3-carboxylic acid methyl ester 
• 871819-39-5 2-methoxycarbonylmethyl-1-methyl-1H-pyrrole-3-carboxylic acid methyl ester 
• 83863-74-5 2-(carboxymethyl)-1-methyl-1H-pyrrole-3-carboxylic acid 

Downstream Products

• 871819-43-1 4-chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid methyl ester 
• 925917-49-3 1-methyl-4-oxo-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid 
• 871819-55-5 4-[(3-chloro-phenyl)-methyl-amino]-1-methyl-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid 
• 871819-38-4 4-(3-chloro-phenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid 
• 871819-53-3 4-(3-chloro-phenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridine-7-carboxylic acid methyl ester 
• 871819-54-4 4-[(3-chloro-phenyl)-methyl-amino ]-1-methyl-1H-pyrrolo[3,2-c]pyridine-7 carboxylic acid methyl ester 
• 925979-47-1 4-(3-chlorophenyl)-1-methyl-7-(4-morpholinylcarbonyl)-1H-pyrrolo[3,2-c]pyridine 
• 925979-09-5 4-[(3-chlorophenyl)oxy]-1-methyl-7-(4-morpholinylcarbonyl)-1H-pyrrolo[3,2-c]pyridine 
• 925917-88-0 4-[(3-chlorophenyl)thio]-1-methyl-7-(1-piperidinylcarbonyl)-1H-pyrrolo[3,2-c]pyridine 
• 925917-89-1 4-[(3-chlorophenyl)sulfonyl]-1-methyl-7-(1-piperidinylcarbonyl)-1H-pyrrolo[3,2-c]pyridine 
• 925979-44-8 N-[(3-chlorophenyl)methyl]-1-methyl-7-(4-morpholinylcarbonyl)-1H-pyrrolo[3,2-c]pyridin-4-amine 
• 925979-45-9 3-chloro-N-[1-methyl-7-(4-morpholinylcarbonyl)-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide 
• 925979-46-0 1-methyl-7-(4-morpholinylcarbonyl)-4-{3-[(trifluoromethyl)oxy]phenyl}-1H-pyrrolo[3,2-c]pyridine 
• 925917-93-7 4-(3-chlorophenyl)-1-methyl-7-(4-morpholinylcarbonyl)-1H-pyrrolo[3,2-c]pyridine hydrochloride 

Relevant articles and documents

Discovery of 1-[4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin- 7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a brain penetrant 5-azaindole CB2 agonist for the treatment of chronic pain

We report the synthesis and SAR of a series of novel azaindole CB 2 agonists. 6-Azaindole 18 showed activity in an acute pain model but was inactive in a chronic model. 18 is a Pgp substrate with low brain penetration. The template was redesign

PYRROLOPYRIDINE DERIVATIVES

The present invention relates to novel pyrrolopyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.