871840-80-1

Basic information

• Product Name: (R)-1-[4-(3-trifluoromethyl-3H-diazirin-3-yl)phenyl]ethylamine
• Synonyms: (R)-1-[4-(3-trifluoromethyl-3H-diazirin-3-yl)phenyl]ethylamine
• CAS NO: 871840-80-1
• Molecular Weight: 229.205
• Mol File: 871840-80-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1-[4-(3-trifluoromethyl-3H-diazirin-3-yl)phenyl]ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-[4-(3-trifluoromethyl-3H-diazirin-3-yl)phenyl]ethylamine(871840-80-1)
• EPA Substance Registry System: (R)-1-[4-(3-trifluoromethyl-3H-diazirin-3-yl)phenyl]ethylamine(871840-80-1)

Safety Data

• Hazardous Substances Data: 871840-80-1(Hazardous Substances Data)

Upstream product

• 24358-62-1 (R)-1-(4-bromophenyl)ethylamine 
• 871841-28-0 (R)-N-(tert-butoxycarbonyl)-1-[4-(3-trifluoromethyl-3H-diazirin-3-yl)phenyl]ethylamine 
• 871841-24-6 (R)-N-(tert-butoxycarbonyl)-4-[(1-amino)ethyl]-2,2,2-trifluoroacetophenone-O-(4-toluenesulfonyl)oxime 
• 871841-22-4 (R)-N-(tert-butoxycarbonyl)-4-[(1-amino)ethyl]-2,2,2-trifluoroacetophenone oxime 
• 871841-26-8 {1-[4-(3-trifluoromethyl-diaziridin-3-yl)-phenyl]-ethyl}-carbamic acid tert-butyl ester 
• 871841-19-9 (R)-N-(tert-butoxycarbonyl)-4-[(1-amino)ethyl]-2,2,2-trifluoroacetophenone 
• 578729-21-2 [(R)-1-(4-bromo-phenyl)-ethyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Preparation of novel 3H-trifluoromethyldiazirine-based photoactivatable potassium channel antagonists

The preparation of a series of photoactivatable precursors for use in photoaffinity labelling of potassium channels is described. 3H-Diazirine functionalities were incorporated into the previously described potassium channel antagonists 1-3. The ability to perform enantioselective reductions and Wittig reactions in the presence of 3H-diazirines was central to this work.