871841-28-0Relevant articles and documents
Preparation of novel 3H-trifluoromethyldiazirine-based photoactivatable potassium channel antagonists
Sanderson, John M.,Findlay, John B. C.,Fishwick, Colin W. G.
, p. 11244 - 11252 (2007/10/03)
The preparation of a series of photoactivatable precursors for use in photoaffinity labelling of potassium channels is described. 3H-Diazirine functionalities were incorporated into the previously described potassium channel antagonists 1-3. The ability to perform enantioselective reductions and Wittig reactions in the presence of 3H-diazirines was central to this work.